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- W2906588691 abstract "Research on test teratogenic effects of ethanol extract of leaves of the soursop ( Annona muricata L.) have been conducted on white mice fetus. Animal experiments are grouped into 4 group consisting of Group I as a negative control only granted suspension of Na CMC 0.5%, Group II, Group III and Group IV granted soursop leaf ethanol extract at a dose of 250 mg / kg, 500 mg / kg, and 1000 mg / kg once daily from day 6 to day 15 of pregnancy. The 18th day of pregnancy mice were dissected. Results of the study at a dose of 250 mg / kg, a dose of 500 mg / kg, a dose of 1000 mg / kg give teratogen effects. A dose of 250 mg / kg, a dose of 500 mg / kg give teratogen effect with the discovery of skeletal abnormalities. A dose of 1000 mg / kg give teratogen effect with the discovery of late growth. Results showed that the ethanol extract of the leaves of the soursop affect weight loss parent mice were significantly (p <0.05) when compared to the negative control. The quantity of fetuses decreased significantly (p <0.05) when compared to the negative control. Fetal body weight showed a significant effect (p <0.05) when compared to the negative control." @default.
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- W2906588691 date "2017-03-02" @default.
- W2906588691 modified "2023-09-26" @default.
- W2906588691 title "Uji Efek Teratogen Ekstrak Etanol Daun Sirsak (Annona muricata L) Terhadap Fetus Mencit Putih" @default.
- W2906588691 doi "https://doi.org/10.52689/higea.v8i1.135" @default.
- W2906588691 hasPublicationYear "2017" @default.
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