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- W2906804908 abstract "Introduction This study investigated the associations between low birth weight (LBW, = 37 gestational weeks) and air pollution by source and composition in California, over the period 2001-2008. Methods Complementary exposure models were used: an empirical Bayesian kriging model for the interpolation of ambient pollutant measurement results, a source-oriented chemical transport model (using California emission inventories) that estimated fine and ultrafine particulate matter (PM) concentrations (4 km* 4 km) by source and composition, a line-source roadway dispersion model at fine resolution, and traffic index estimates. Birth weight was obtained from the California birth certificate records. Five controls per LBW case were randomly selected (without matching or stratification). The resulting case-control datasets were analyzed by logistic regression with random effect per hospital, using generalized additive mixed models adjusted for race/ethnicity, education, maternal age and household income. Results In total 72,632 LBW cases were included. LBW was positively associated with interpolated measurements of ozone but not total fine PM or nitrogen dioxide. No significant association was observed between term LBW and primary PM from all sources grouped together. However, LBW risk was positively associated with primary PM emitted by on-road gasoline and diesel or by commercial meat cooking sources. Primary PM from wood burning was inversely associated with LBW. Positive associations (respectively significant and close to significant) were observed for secondary organic aerosols and nitrates. LBW was positively associated with ultrafine particle numbers modeled with the line-source roadway dispersion model, and with traffic density. Discussion This large study based on complementary exposure metrics points to primary pollution sources (traffic and commercial meat cooking) but also to secondary pollutants as risk factors for LBW." @default.
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- W2906804908 date "2015-08-20" @default.
- W2906804908 modified "2023-09-26" @default.
- W2906804908 title "Exposure To Multiple Sources And Components Of Air Pollution And Low Birth Weight In California, 2001-2008." @default.
- W2906804908 doi "https://doi.org/10.1289/isee.2015.2015-711" @default.
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