Matches in SemOpenAlex for { <https://semopenalex.org/work/W2906929042> ?p ?o ?g. }
- W2906929042 endingPage "404" @default.
- W2906929042 startingPage "395" @default.
- W2906929042 abstract "Objectives: Emerging evidence suggests that social networks may protect against the development of dementia among older adults. In this study we analysed the association between social networks, the apolipoprotein E (APOE) ε4 allele, and dementia. We also investigated whether there were gender-specific patterns in this respect.Method: The analyses used population-based longitudinal data from Gothenburg, Sweden: the H70 Birth Cohort Study and the Prospective Population Study on Women (PPSW). A total of 580 individuals born in 1930 underwent semi-structured neuropsychiatric examinations in 2000–2001. Follow-up examinations were carried out in 2005–2006 and 2009–2010. The timing of dementia onset was analysed using Cox proportional hazards regression.Results: The presence of the APOE ε4 allele affected the risk of developing dementia in both genders. Among women, distant social networks had a protective effect on dementia, while among men the significant associations between close social networks and dementia did not remain after controlling for covariates. Significant interactions between social networks and the APOE ε4 allele were not found.Conclusion: Strong social networks do not seem to moderate the increased risk of dementia implied by the APOE ε4 allele. Nevertheless, our results underline the importance of strong social networks in postponing dementia onset and indicate that their impact may differ among men and women." @default.
- W2906929042 created "2019-01-11" @default.
- W2906929042 creator A5007974703 @default.
- W2906929042 creator A5022082970 @default.
- W2906929042 creator A5030376255 @default.
- W2906929042 creator A5046997994 @default.
- W2906929042 creator A5058286274 @default.
- W2906929042 creator A5068394264 @default.
- W2906929042 creator A5079766290 @default.
- W2906929042 date "2018-12-27" @default.
- W2906929042 modified "2023-10-17" @default.
- W2906929042 title "The impact of social networks and <i>APOE</i> ε4 on dementia among older adults: tests of possible interactions" @default.
- W2906929042 cites W1579590134 @default.
- W2906929042 cites W1635983300 @default.
- W2906929042 cites W1820863330 @default.
- W2906929042 cites W1870043354 @default.
- W2906929042 cites W1929876078 @default.
- W2906929042 cites W1965812118 @default.
- W2906929042 cites W1971029328 @default.
- W2906929042 cites W1971905047 @default.
- W2906929042 cites W1972025839 @default.
- W2906929042 cites W1976949208 @default.
- W2906929042 cites W1977775666 @default.
- W2906929042 cites W1978181225 @default.
- W2906929042 cites W1991942969 @default.
- W2906929042 cites W1995785495 @default.
- W2906929042 cites W2000781871 @default.
- W2906929042 cites W2001216145 @default.
- W2906929042 cites W2007561278 @default.
- W2906929042 cites W2012611625 @default.
- W2906929042 cites W2018856970 @default.
- W2906929042 cites W2022072606 @default.
- W2906929042 cites W2024778887 @default.
- W2906929042 cites W2034897558 @default.
- W2906929042 cites W2036362108 @default.
- W2906929042 cites W2041378923 @default.
- W2906929042 cites W2043223781 @default.
- W2906929042 cites W2044013499 @default.
- W2906929042 cites W2048104409 @default.
- W2906929042 cites W2054814767 @default.
- W2906929042 cites W2063873618 @default.
- W2906929042 cites W2069272002 @default.
- W2906929042 cites W2070465767 @default.
- W2906929042 cites W2072540088 @default.
- W2906929042 cites W2072934963 @default.
- W2906929042 cites W2076216415 @default.
- W2906929042 cites W2078885108 @default.
- W2906929042 cites W2080844455 @default.
- W2906929042 cites W2082405652 @default.
- W2906929042 cites W2093144777 @default.
- W2906929042 cites W2098516684 @default.
- W2906929042 cites W2099304543 @default.
- W2906929042 cites W2101410989 @default.
- W2906929042 cites W2102782858 @default.
- W2906929042 cites W2102796951 @default.
- W2906929042 cites W2103860290 @default.
- W2906929042 cites W2103993711 @default.
- W2906929042 cites W2106159603 @default.
- W2906929042 cites W2106916357 @default.
- W2906929042 cites W2107381357 @default.
- W2906929042 cites W2112147894 @default.
- W2906929042 cites W2114233866 @default.
- W2906929042 cites W2117625001 @default.
- W2906929042 cites W2128711456 @default.
- W2906929042 cites W2131920984 @default.
- W2906929042 cites W2133525395 @default.
- W2906929042 cites W2134570333 @default.
- W2906929042 cites W2140884566 @default.
- W2906929042 cites W2142097601 @default.
- W2906929042 cites W2144617542 @default.
- W2906929042 cites W2144907160 @default.
- W2906929042 cites W2147968429 @default.
- W2906929042 cites W2148553720 @default.
- W2906929042 cites W2149486086 @default.
- W2906929042 cites W2151217555 @default.
- W2906929042 cites W2151349305 @default.
- W2906929042 cites W2152347610 @default.
- W2906929042 cites W2157984263 @default.
- W2906929042 cites W2161290803 @default.
- W2906929042 cites W2162294947 @default.
- W2906929042 cites W2168357345 @default.
- W2906929042 cites W2170519037 @default.
- W2906929042 cites W2327427660 @default.
- W2906929042 cites W2330398304 @default.
- W2906929042 cites W2341205300 @default.
- W2906929042 cites W2397352117 @default.
- W2906929042 cites W2530805098 @default.
- W2906929042 cites W2546814200 @default.
- W2906929042 cites W2588930452 @default.
- W2906929042 cites W2769602825 @default.
- W2906929042 cites W2800941687 @default.
- W2906929042 cites W4211156109 @default.
- W2906929042 cites W4233622592 @default.
- W2906929042 cites W4300944136 @default.
- W2906929042 doi "https://doi.org/10.1080/13607863.2018.1531368" @default.
- W2906929042 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30587010" @default.
- W2906929042 hasPublicationYear "2018" @default.
- W2906929042 type Work @default.