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- W2907009024 abstract "Several retinal conditions have been recently revealed by optical coherence tomography (OCT) to occur more frequently in glaucoma than in healthy eyes: paravascular defects, peripapillary retinoschisis, and pseudo-cysts of the inner nuclear layer (INL). Here the clinical OCT findings described in these reports are reviewed and a framework that could explain why they are related and occur more frequently in glaucoma is proposed. Evidence suggests that these conditions all share in common a strong tendency to develop in association with severe and/or rapidly progressing disease and a likelihood of involving biomechanical forces and differential tissue deformation. Müller glia are mechanosensitive and known to react to shear and axial strain, and to participate in homeostasis of water and ion flux through the retina, and to provide spring-like capability to buffer of mechanical forces. Thus, Müller cell integrity is also likely to be involved in the development and/or response to such events. OCT has also revealed that Müller cell optical properties (scatter and attenuation) appear to be altered in at least two of these retinal conditions: peripapillary retinoschisis and pseudo-cysts of the INL. Future studies applying 3D strain mapping techniques might reveal structural changes over time (either acute or longer-term deformations) that predict the onset and location of these retinal defects and their relationship to progressive optic nerve head deformation, retinal nerve fiber layer, and retinal ganglion cell loss in glaucoma." @default.
- W2907009024 created "2019-01-11" @default.
- W2907009024 creator A5032073359 @default.
- W2907009024 date "2019-01-02" @default.
- W2907009024 modified "2023-10-05" @default.
- W2907009024 title "Pulling and Tugging on the Retina: Mechanical Impact of Glaucoma Beyond the Optic Nerve Head" @default.
- W2907009024 cites W1034109569 @default.
- W2907009024 cites W1576427652 @default.
- W2907009024 cites W1963991039 @default.
- W2907009024 cites W1964458657 @default.
- W2907009024 cites W1966873113 @default.
- W2907009024 cites W1969824248 @default.
- W2907009024 cites W1974324457 @default.
- W2907009024 cites W1976368026 @default.
- W2907009024 cites W1980368328 @default.
- W2907009024 cites W1987041755 @default.
- W2907009024 cites W1987502158 @default.
- W2907009024 cites W1992947049 @default.
- W2907009024 cites W1997936295 @default.
- W2907009024 cites W1998964910 @default.
- W2907009024 cites W2000511084 @default.
- W2907009024 cites W2001499672 @default.
- W2907009024 cites W2032445406 @default.
- W2907009024 cites W2033982648 @default.
- W2907009024 cites W2036302917 @default.
- W2907009024 cites W2040751395 @default.
- W2907009024 cites W2047268748 @default.
- W2907009024 cites W2050232773 @default.
- W2907009024 cites W2057665534 @default.
- W2907009024 cites W2061183885 @default.
- W2907009024 cites W2064036669 @default.
- W2907009024 cites W2072560781 @default.
- W2907009024 cites W2075612202 @default.
- W2907009024 cites W2084534667 @default.
- W2907009024 cites W2086060490 @default.
- W2907009024 cites W2092043772 @default.
- W2907009024 cites W2093007223 @default.
- W2907009024 cites W2099379703 @default.
- W2907009024 cites W2110964437 @default.
- W2907009024 cites W2127294620 @default.
- W2907009024 cites W2130075876 @default.
- W2907009024 cites W2142628309 @default.
- W2907009024 cites W2151289611 @default.
- W2907009024 cites W2154221129 @default.
- W2907009024 cites W2160481760 @default.
- W2907009024 cites W2163925135 @default.
- W2907009024 cites W2188669542 @default.
- W2907009024 cites W2206439320 @default.
- W2907009024 cites W2299401824 @default.
- W2907009024 cites W2311160959 @default.
- W2907009024 cites W2314432796 @default.
- W2907009024 cites W2325470948 @default.
- W2907009024 cites W2331050744 @default.
- W2907009024 cites W2331578519 @default.
- W2907009024 cites W2369799003 @default.
- W2907009024 cites W2426471822 @default.
- W2907009024 cites W2464894252 @default.
- W2907009024 cites W2508760412 @default.
- W2907009024 cites W2517536335 @default.
- W2907009024 cites W2523512471 @default.
- W2907009024 cites W2553236212 @default.
- W2907009024 cites W2576903091 @default.
- W2907009024 cites W2583383498 @default.
- W2907009024 cites W2587948757 @default.
- W2907009024 cites W2592110621 @default.
- W2907009024 cites W2593094098 @default.
- W2907009024 cites W2601859851 @default.
- W2907009024 cites W2608096531 @default.
- W2907009024 cites W2731981825 @default.
- W2907009024 cites W2736398029 @default.
- W2907009024 cites W2746660828 @default.
- W2907009024 cites W2769517586 @default.
- W2907009024 cites W2770144792 @default.
- W2907009024 cites W2770233253 @default.
- W2907009024 cites W2782845052 @default.
- W2907009024 cites W2783125960 @default.
- W2907009024 cites W2788786482 @default.
- W2907009024 cites W2791267416 @default.
- W2907009024 cites W2802347572 @default.
- W2907009024 cites W2803587066 @default.
- W2907009024 cites W2807528943 @default.
- W2907009024 cites W2810189966 @default.
- W2907009024 cites W2886499951 @default.
- W2907009024 cites W2886715687 @default.
- W2907009024 cites W2891466898 @default.
- W2907009024 cites W302579078 @default.
- W2907009024 cites W4232005894 @default.
- W2907009024 doi "https://doi.org/10.1167/iovs.18-25837" @default.
- W2907009024 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30601928" @default.
- W2907009024 hasPublicationYear "2019" @default.
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