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• W2907029448 abstract "A new 6-benzyl-γ-pyrone (1), named aspergyllone was isolated from the culture filtrates of an endolichenic fungus Aspergillus niger Tiegh, obtained from lichen thallus Parmotrema ravum (Krog & Swinscow) Serus, collected in India. 1 was isolated for the first time from an endolichenic fungus together with six other known metabolites identified as aurasperones A (2) and D (3), asperpyrone A (4), fonsecinone A (5), carbonarone A (6) and pyrophen (7). The compounds were tested against a panel of human, plant, food borne and fish pathogens. Aspergyllone showed strong selective antifungal activity against Candida parapsilosis (Ashford) Langeron & Talice, with an IC50 of 52 µg/mL. Aurasperone A and pyrophen showed moderate to strong antimicrobial activity inhibiting seven different test pathogens, being pyrophen active with IC50 ranging from 35 to 97 µg/mL." @default.
• W2907029448 created "2019-01-11" @default.
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• W2907029448 date "2019-01-02" @default.
• W2907029448 modified "2023-10-16" @default.
• W2907029448 title "Antimicrobial secondary metabolites of an endolichenic <i>Aspergillus niger</i> isolated from lichen thallus of <i>Parmotrema ravum</i>" @default.
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• W2907029448 doi "https://doi.org/10.1080/14786419.2018.1544982" @default.
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