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- W2907177777 abstract "DNA microsatellites are genetic markers that can be useful in addressing questions at a variety of scales, ranging from the extremely fine grained to the fairly coarse grained. More specifically, this genetic tool can help solve problems ranging from individual-specific, such as determining gender, to questions of relatedness and parentage. The rise of polymerase chain reaction (PCR)-based microsatellite markers provides abundant opportunities but also calls for caution. Because of their suitability for addressing problems at a fairly wide range of levels of organization from within individuals to among populations or species, a considerable expansion of interest in the interactions across these scales is foreseen. Differences in mutation processes and rates between microsatellites and allozymes provide both opportunities and problems for analysis of population subdivision. In allozyme analyses, new alleles arise by point mutations, and allelic variation has usually been modeled under the assumption of infinite alleles. The need for careful assessment of the fit among the demographic parameters of the population analyzed (migration, drift, mutation rate) and the assumptions of the models used to analyze it cannot be overemphasized. Application of an inappropriate model can lead to the wrong conclusions about the patterns and processes of genetic differentiation." @default.
- W2907177777 created "2019-01-11" @default.
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- W2907177777 creator A5035220521 @default.
- W2907177777 date "1997-01-01" @default.
- W2907177777 modified "2023-09-27" @default.
- W2907177777 title "DNA Microsatellites as Genetic Markers at Several Scales" @default.
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- W2907177777 doi "https://doi.org/10.1016/b978-012498315-1/50003-0" @default.
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