Matches in SemOpenAlex for { <https://semopenalex.org/work/W2907339512> ?p ?o ?g. }
- W2907339512 endingPage "60" @default.
- W2907339512 startingPage "48" @default.
- W2907339512 abstract "Abstract Introduction Suicidality and self-injurious behavior afflict patients with a wide variety of psychiatric illnesses. Currently, there are few pharmacologic treatments for suicidality and self-injurious behavior and none that treat these conditions emergently. Recently, ketamine has demonstrated efficacy in treating both depression and acute suicidal ideation. An increasing usage of ketamine, of a variety of formulations, has been studied for these indications. This article reviews the evidence for use of ketamine in self-injurious behavior and suicidality. Methods A review of the MEDLINE database for articles relating to ketamine, self-injurious behavior, suicidality, and self-harm was conducted. Additional articles were assessed via cross-reference. Results A total of 24 articles that included clinical trials, meta-analyses, case series, and case reports were analyzed. The majority of studies of ketamine for suicidal ideation include the intravenous route using a dose of 0.5 mg/kg over 40 minutes. These studies suggest that intravenous ketamine may be effective at reducing suicidal ideation acutely. Data on use of ketamine in the intramuscular, intranasal, and oral forms are limited and of poorer quality. Studies on these formulations contain greater variability of positive and negative results of ketamine for reducing suicidality and self-injurious behavior. The durability of the antisuicidal effects across all formulations is limited. Discussion Ketamine may be an effective option for the treatment of suicidal ideation in patients across inpatient, outpatient, or emergent settings. At this time, more research is needed on the efficacy of ketamine across all formulations being used in clinical practice." @default.
- W2907339512 created "2019-01-11" @default.
- W2907339512 creator A5034672213 @default.
- W2907339512 creator A5087782225 @default.
- W2907339512 date "2019-01-01" @default.
- W2907339512 modified "2023-10-15" @default.
- W2907339512 title "The effects of ketamine on suicidality across various formulations and study settings" @default.
- W2907339512 cites W1123766524 @default.
- W2907339512 cites W1865092458 @default.
- W2907339512 cites W1970133878 @default.
- W2907339512 cites W1977485030 @default.
- W2907339512 cites W1977822213 @default.
- W2907339512 cites W2003960536 @default.
- W2907339512 cites W2004678922 @default.
- W2907339512 cites W2014323482 @default.
- W2907339512 cites W2016429796 @default.
- W2907339512 cites W2044440339 @default.
- W2907339512 cites W2053819528 @default.
- W2907339512 cites W2057804290 @default.
- W2907339512 cites W2067495470 @default.
- W2907339512 cites W2070466479 @default.
- W2907339512 cites W2072878669 @default.
- W2907339512 cites W2098188756 @default.
- W2907339512 cites W2106332132 @default.
- W2907339512 cites W2114613490 @default.
- W2907339512 cites W2118815581 @default.
- W2907339512 cites W2123476505 @default.
- W2907339512 cites W2131823335 @default.
- W2907339512 cites W2145055644 @default.
- W2907339512 cites W2160051587 @default.
- W2907339512 cites W2219380992 @default.
- W2907339512 cites W2260799978 @default.
- W2907339512 cites W2289004134 @default.
- W2907339512 cites W2519728323 @default.
- W2907339512 cites W2559576040 @default.
- W2907339512 cites W2577277498 @default.
- W2907339512 cites W2592351415 @default.
- W2907339512 cites W2597843020 @default.
- W2907339512 cites W2602793133 @default.
- W2907339512 cites W2608506675 @default.
- W2907339512 cites W2610419759 @default.
- W2907339512 cites W2731109846 @default.
- W2907339512 cites W2737966001 @default.
- W2907339512 cites W2740797966 @default.
- W2907339512 cites W2762798648 @default.
- W2907339512 cites W2767463537 @default.
- W2907339512 cites W2769952361 @default.
- W2907339512 cites W2770852547 @default.
- W2907339512 cites W2771797851 @default.
- W2907339512 cites W2790556778 @default.
- W2907339512 cites W2792882327 @default.
- W2907339512 cites W2796940952 @default.
- W2907339512 cites W2912647520 @default.
- W2907339512 cites W496281 @default.
- W2907339512 doi "https://doi.org/10.9740/mhc.2019.01.048" @default.
- W2907339512 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6322816" @default.
- W2907339512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30627504" @default.
- W2907339512 hasPublicationYear "2019" @default.
- W2907339512 type Work @default.
- W2907339512 sameAs 2907339512 @default.
- W2907339512 citedByCount "33" @default.
- W2907339512 countsByYear W29073395122019 @default.
- W2907339512 countsByYear W29073395122020 @default.
- W2907339512 countsByYear W29073395122021 @default.
- W2907339512 countsByYear W29073395122022 @default.
- W2907339512 countsByYear W29073395122023 @default.
- W2907339512 crossrefType "journal-article" @default.
- W2907339512 hasAuthorship W2907339512A5034672213 @default.
- W2907339512 hasAuthorship W2907339512A5087782225 @default.
- W2907339512 hasBestOaLocation W29073395121 @default.
- W2907339512 hasConcept C118552586 @default.
- W2907339512 hasConcept C126322002 @default.
- W2907339512 hasConcept C139719470 @default.
- W2907339512 hasConcept C162324750 @default.
- W2907339512 hasConcept C177713679 @default.
- W2907339512 hasConcept C2776641880 @default.
- W2907339512 hasConcept C2776867660 @default.
- W2907339512 hasConcept C2780795376 @default.
- W2907339512 hasConcept C3017944768 @default.
- W2907339512 hasConcept C526869908 @default.
- W2907339512 hasConcept C535046627 @default.
- W2907339512 hasConcept C545542383 @default.
- W2907339512 hasConcept C70410870 @default.
- W2907339512 hasConcept C71924100 @default.
- W2907339512 hasConceptScore W2907339512C118552586 @default.
- W2907339512 hasConceptScore W2907339512C126322002 @default.
- W2907339512 hasConceptScore W2907339512C139719470 @default.
- W2907339512 hasConceptScore W2907339512C162324750 @default.
- W2907339512 hasConceptScore W2907339512C177713679 @default.
- W2907339512 hasConceptScore W2907339512C2776641880 @default.
- W2907339512 hasConceptScore W2907339512C2776867660 @default.
- W2907339512 hasConceptScore W2907339512C2780795376 @default.
- W2907339512 hasConceptScore W2907339512C3017944768 @default.
- W2907339512 hasConceptScore W2907339512C526869908 @default.
- W2907339512 hasConceptScore W2907339512C535046627 @default.
- W2907339512 hasConceptScore W2907339512C545542383 @default.
- W2907339512 hasConceptScore W2907339512C70410870 @default.
- W2907339512 hasConceptScore W2907339512C71924100 @default.