FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2907426545> ?p ?o ?g. }

• W2907426545 abstract "Background: Many authors found that dexmedetomidine is an effective, safe drug for sedation during extracorporeal shock wave lithotripsy (ESWL). Dexmedetomidine is a lipophilic α2- agonist ,which sedates patients by reducing sympathetic activity and the level of arousal ,thus patients lie calmly in beds but are easily roused to full consciousness. In the present study, the sedative, haemodynamics, and respiratory effects, and recovery time of dexmedetomidine and dexmedetomidine/fentanyl combination were compared to one of the commonly used sedative analgesic regimen (midazolam/fentanyl) in patients undergoing lithotripsy. Methods: Sixty ASA I - II patients undergoing (ESWL) were divided into three equal groups and were randomized to receive either dexmedetomidine (dex group), dexmedetomidine fentanyl combination (dex/fentanyl group) or midazolam fentanyl (midazolam/fentanyl group) . In dex group: Initial loading dose of dex 1 μg/kg was infused for 10 min followed by continuous infusion 0.1-0.7 μg/kg/h. In dex/fentanyl group, initial dose of 1 μg/kg dex was infused over 10 min followed by continuous infusion 0.1-0.7 μg/kg/h. At the same time, fentanyl infusion started 1 μg/kg over 10 min. In midazolam/fenatnyl group, midazolam 0.05 mg/kg and fentanyl 1 μg/kg were infused over 10 min followed by continuous infusion of normal saline. Heart rate (HR), mean arterial pressure (MAP), oxygen saturation (SpO2), and respiratory rate were recorded. Pain intensity was evaluated with a visual analog scale. Depth of sedation was monitored using Ramsay sedation score (RSS). Recovery time, rescue analgesic and sedative were recorded. Results: In all groups, no significant changes in oxygen saturation and respiratory rate were observed. In dex and dex/fentanyl groups there was a significant decrease in heart rate and mean arterial pressure during and post procedure. Supplemental fentanyl was required in 80% of patients in dex group to achieve a satisfactory level of analgesia (vs. 25% of patients in dex/fentanyl group and 40% of patients in midazolam/fentanyl group). Also 70% of patients in dex group received rescue midazolam vs. 15% in dex/fentanyl group and 20% in midazolam/fentanyl group. Time to home readiness was longer in dex,and dex/fentanyl groups than in midazolam/fentanyl group(80, 75, and 44 min), respectively. Conclusion: Dexmedetomidine alone does not appear to be suitable for sedation in patients undergoing ESWL. Combination of dexmedetomidine with fentanyl can be used safely and effectively for sedation and analgesia during ESWL, so it could be an alternative to conventional midazolam/fentanyl regimen but it is associated with longer recovery time." @default.
• W2907426545 created "2019-01-11" @default.
• W2907426545 creator A5075756691 @default.
• W2907426545 date "2009-10-01" @default.
• W2907426545 modified "2023-09-24" @default.
• W2907426545 title "Comparative Study of Three Sedative Techniques During Shock Wave Lithotripsy." @default.
• W2907426545 cites W1582968414 @default.
• W2907426545 cites W1976653029 @default.
• W2907426545 cites W1977333903 @default.
• W2907426545 cites W1997421395 @default.
• W2907426545 cites W2022106209 @default.
• W2907426545 cites W2073279176 @default.
• W2907426545 cites W2125134115 @default.
• W2907426545 cites W2137550251 @default.
• W2907426545 cites W2160041196 @default.
• W2907426545 doi "https://doi.org/10.21608/ejhm.2009.17473" @default.
• W2907426545 hasPublicationYear "2009" @default.
• W2907426545 type Work @default.
• W2907426545 sameAs 2907426545 @default.
• W2907426545 citedByCount "0" @default.
• W2907426545 crossrefType "journal-article" @default.
• W2907426545 hasAuthorship W2907426545A5075756691 @default.
• W2907426545 hasBestOaLocation W29074265451 @default.
• W2907426545 hasConcept C126322002 @default.
• W2907426545 hasConcept C141071460 @default.
• W2907426545 hasConcept C2776452961 @default.
• W2907426545 hasConcept C2776814716 @default.
• W2907426545 hasConcept C2777602617 @default.
• W2907426545 hasConcept C2777628635 @default.
• W2907426545 hasConcept C2777756408 @default.
• W2907426545 hasConcept C2777950166 @default.
• W2907426545 hasConcept C2777953023 @default.
• W2907426545 hasConcept C2778000748 @default.
• W2907426545 hasConcept C2778384902 @default.
• W2907426545 hasConcept C2781072394 @default.
• W2907426545 hasConcept C2781302539 @default.
• W2907426545 hasConcept C42219234 @default.
• W2907426545 hasConcept C71924100 @default.
• W2907426545 hasConcept C84393581 @default.
• W2907426545 hasConceptScore W2907426545C126322002 @default.
• W2907426545 hasConceptScore W2907426545C141071460 @default.
• W2907426545 hasConceptScore W2907426545C2776452961 @default.
• W2907426545 hasConceptScore W2907426545C2776814716 @default.
• W2907426545 hasConceptScore W2907426545C2777602617 @default.
• W2907426545 hasConceptScore W2907426545C2777628635 @default.
• W2907426545 hasConceptScore W2907426545C2777756408 @default.
• W2907426545 hasConceptScore W2907426545C2777950166 @default.
• W2907426545 hasConceptScore W2907426545C2777953023 @default.
• W2907426545 hasConceptScore W2907426545C2778000748 @default.
• W2907426545 hasConceptScore W2907426545C2778384902 @default.
• W2907426545 hasConceptScore W2907426545C2781072394 @default.
• W2907426545 hasConceptScore W2907426545C2781302539 @default.
• W2907426545 hasConceptScore W2907426545C42219234 @default.
• W2907426545 hasConceptScore W2907426545C71924100 @default.
• W2907426545 hasConceptScore W2907426545C84393581 @default.
• W2907426545 hasLocation W29074265451 @default.
• W2907426545 hasOpenAccess W2907426545 @default.
• W2907426545 hasPrimaryLocation W29074265451 @default.
• W2907426545 hasRelatedWork W2015648663 @default.
• W2907426545 hasRelatedWork W2071041419 @default.
• W2907426545 hasRelatedWork W2118303527 @default.
• W2907426545 hasRelatedWork W2137550251 @default.
• W2907426545 hasRelatedWork W2186398722 @default.
• W2907426545 hasRelatedWork W2286705381 @default.
• W2907426545 hasRelatedWork W2343258447 @default.
• W2907426545 hasRelatedWork W2353454270 @default.
• W2907426545 hasRelatedWork W2370451052 @default.
• W2907426545 hasRelatedWork W2376939397 @default.
• W2907426545 hasRelatedWork W2377082122 @default.
• W2907426545 hasRelatedWork W2377537790 @default.
• W2907426545 hasRelatedWork W2380628352 @default.
• W2907426545 hasRelatedWork W2384922397 @default.
• W2907426545 hasRelatedWork W2386984471 @default.
• W2907426545 hasRelatedWork W2387180402 @default.
• W2907426545 hasRelatedWork W2393384454 @default.
• W2907426545 hasRelatedWork W2520630385 @default.
• W2907426545 hasRelatedWork W2924211529 @default.
• W2907426545 hasRelatedWork W3212247066 @default.
• W2907426545 isParatext "false" @default.
• W2907426545 isRetracted "false" @default.
• W2907426545 magId "2907426545" @default.
• W2907426545 workType "article" @default.