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- W2907446770 abstract "Abstract There are many biologic factors that may influence the adverse effect of a drug, chemical, or substance in mammalian organisms. This chapter describes the basic concepts of protein receptors and chemical interactions and the possible adverse biological consequences of these interactions. Chemical absorption, translocation, and elimination, and extracellular, cellular, and subcellular compartmentalization of substances is explained and illustrated. Basic concepts of chemical bioaccumulation and storage are presented, in addition to the phenomenon of chemical/drug tolerance and organ functional reserve capacity following tissue injury in mammalian organisms." @default.
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- W2907446770 date "2020-01-01" @default.
- W2907446770 modified "2023-09-23" @default.
- W2907446770 title "Biologic factors that influence toxicity" @default.
- W2907446770 doi "https://doi.org/10.1016/b978-0-12-815921-7.00003-x" @default.
- W2907446770 hasPublicationYear "2020" @default.
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