FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2907612455> ?p ?o ?g. }

• W2907612455 endingPage "507" @default.
• W2907612455 startingPage "501" @default.
• W2907612455 abstract "Background Chronic rhinosinusitis (CRS), in particular with nasal polyps (CRSwNP), has been linked with skewed T‐helper 2 and immunoglobulin E (IgE)‐mediated allergic responses. The role of atopy in CRS, however, remains unclear. Correlations between immunological allergic markers and patient‐reported outcomes measures (PROMs) were investigated. Methods A cross‐sectional study of adult patients with CRS undergoing endoscopic sinus surgery was conducted. Immunological allergic markers included automated immunoassay testing for serum‐specific IgE to common allergens (house dust mite, grass, mold, animal epithelia) and total IgE. PROMs were assessed using the 22‐item Sino‐Nasal Outcome Test (SNOT‐22). Patients were defined as atopic based on either a positive specific IgE or elevated total IgE (>160 kU/L). Results A total of 446 patients (45.7% female, age 49.05 ± 14.96 years) were recruited, of which 42.8% had asthma, 51.6% had CRSwNP, and 63.0% had eosinophilic CRS. Positive allergen sensitization was detected in 52.9% patients. Total IgE levels were elevated in 28.0% with mean IgE level of 161 ± 269 kU/L. Atopy was associated with younger age at the time of surgery, CRSwNP, asthma, and eosinophilic CRS (eCRS). Atopy was also associated with increased severity in nasal symptom score (13.1 ± 6.4 vs 11.9 ± 6.0, p = 0.04), as well as worse scores in the loss of smell/taste (χ 2 (1) = 5.97, p = 0.02) and need to blow nose (χ 2 (1) = 4.26, p = 0.04) questions in the CRS population. In the CRSwNP population, there was no significant association between atopy and PROMs. Conclusion Comorbid atopy in CRS is associated with additional symptom burden, reflected mainly within the nasal symptom quality of life markers. Atopy assessment in CRS is important to ensure appropriate and successful treatment of the disease." @default.
• W2907612455 created "2019-01-11" @default.
• W2907612455 creator A5016147964 @default.
• W2907612455 creator A5049555902 @default.
• W2907612455 creator A5075849875 @default.
• W2907612455 creator A5082865827 @default.
• W2907612455 creator A5091094792 @default.
• W2907612455 date "2019-01-03" @default.
• W2907612455 modified "2023-10-16" @default.
• W2907612455 title "Atopy in chronic rhinosinusitis: impact on quality of life outcomes" @default.
• W2907612455 cites W1591052090 @default.
• W2907612455 cites W1927647456 @default.
• W2907612455 cites W1957314586 @default.
• W2907612455 cites W1965887944 @default.
• W2907612455 cites W1969063775 @default.
• W2907612455 cites W1970196744 @default.
• W2907612455 cites W1982941253 @default.
• W2907612455 cites W1999270449 @default.
• W2907612455 cites W2004627112 @default.
• W2907612455 cites W2006184226 @default.
• W2907612455 cites W2030674948 @default.
• W2907612455 cites W2039774344 @default.
• W2907612455 cites W2052996336 @default.
• W2907612455 cites W2105880697 @default.
• W2907612455 cites W2124635861 @default.
• W2907612455 cites W2126447485 @default.
• W2907612455 cites W2128713195 @default.
• W2907612455 cites W2138092276 @default.
• W2907612455 cites W2165726810 @default.
• W2907612455 cites W2173089643 @default.
• W2907612455 cites W2217578641 @default.
• W2907612455 cites W2379051324 @default.
• W2907612455 cites W2413064995 @default.
• W2907612455 cites W2794907263 @default.
• W2907612455 cites W2807013077 @default.
• W2907612455 doi "https://doi.org/10.1002/alr.22272" @default.
• W2907612455 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30604578" @default.
• W2907612455 hasPublicationYear "2019" @default.
• W2907612455 type Work @default.
• W2907612455 sameAs 2907612455 @default.
• W2907612455 citedByCount "18" @default.
• W2907612455 countsByYear W29076124552019 @default.
• W2907612455 countsByYear W29076124552020 @default.
• W2907612455 countsByYear W29076124552021 @default.
• W2907612455 countsByYear W29076124552022 @default.
• W2907612455 countsByYear W29076124552023 @default.
• W2907612455 crossrefType "journal-article" @default.
• W2907612455 hasAuthorship W2907612455A5016147964 @default.
• W2907612455 hasAuthorship W2907612455A5049555902 @default.
• W2907612455 hasAuthorship W2907612455A5075849875 @default.
• W2907612455 hasAuthorship W2907612455A5082865827 @default.
• W2907612455 hasAuthorship W2907612455A5091094792 @default.
• W2907612455 hasConcept C126322002 @default.
• W2907612455 hasConcept C141071460 @default.
• W2907612455 hasConcept C141105273 @default.
• W2907612455 hasConcept C142724271 @default.
• W2907612455 hasConcept C159654299 @default.
• W2907612455 hasConcept C203014093 @default.
• W2907612455 hasConcept C207480886 @default.
• W2907612455 hasConcept C2776042228 @default.
• W2907612455 hasConcept C2777697326 @default.
• W2907612455 hasConcept C2777768476 @default.
• W2907612455 hasConcept C2778166374 @default.
• W2907612455 hasConcept C2778311950 @default.
• W2907612455 hasConcept C2779758542 @default.
• W2907612455 hasConcept C2780510475 @default.
• W2907612455 hasConcept C2781390199 @default.
• W2907612455 hasConcept C2908647359 @default.
• W2907612455 hasConcept C3019717275 @default.
• W2907612455 hasConcept C71924100 @default.
• W2907612455 hasConcept C90924648 @default.
• W2907612455 hasConcept C99454951 @default.
• W2907612455 hasConceptScore W2907612455C126322002 @default.
• W2907612455 hasConceptScore W2907612455C141071460 @default.
• W2907612455 hasConceptScore W2907612455C141105273 @default.
• W2907612455 hasConceptScore W2907612455C142724271 @default.
• W2907612455 hasConceptScore W2907612455C159654299 @default.
• W2907612455 hasConceptScore W2907612455C203014093 @default.
• W2907612455 hasConceptScore W2907612455C207480886 @default.
• W2907612455 hasConceptScore W2907612455C2776042228 @default.
• W2907612455 hasConceptScore W2907612455C2777697326 @default.
• W2907612455 hasConceptScore W2907612455C2777768476 @default.
• W2907612455 hasConceptScore W2907612455C2778166374 @default.
• W2907612455 hasConceptScore W2907612455C2778311950 @default.
• W2907612455 hasConceptScore W2907612455C2779758542 @default.
• W2907612455 hasConceptScore W2907612455C2780510475 @default.
• W2907612455 hasConceptScore W2907612455C2781390199 @default.
• W2907612455 hasConceptScore W2907612455C2908647359 @default.
• W2907612455 hasConceptScore W2907612455C3019717275 @default.
• W2907612455 hasConceptScore W2907612455C71924100 @default.
• W2907612455 hasConceptScore W2907612455C90924648 @default.
• W2907612455 hasConceptScore W2907612455C99454951 @default.
• W2907612455 hasIssue "5" @default.
• W2907612455 hasLocation W29076124551 @default.
• W2907612455 hasLocation W29076124552 @default.
• W2907612455 hasOpenAccess W2907612455 @default.
• W2907612455 hasPrimaryLocation W29076124551 @default.
• W2907612455 hasRelatedWork W2954334734 @default.

• next