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• W2907720121 abstract "The role of serum vitamin D (Vit D) in cardiometabolic and muscle health remains unclear. The study aimed to evaluate associations of Vit D and factors of healthy aging among community-living middle-aged and older people in Taiwan. Analytic data on 1839 community-living older adults were excerpted from I-Lan Longitudinal Aging Study. All participants were collected demographic characteristics, serum Vit D, functional assessment, and cardiometabolic risk factors. The prevalence of Vit D insufficiency and deficiency in this study was 50.5% and 33.6%, respectively. Among 617 participants with Vit D deficiency, 72.3% of them were women. In multivariate logistic regression, the independent risk factors of Vit D deficiency were male gender (odds ratio [OR]: 0.266; 95% confidence interval [CI]: 0.213-0.333; P < 0.001), higher BMI (OR: 1.036; 95% CI: 1.005-1.067; P = 0.022), high total cholesterol (OR: 1.437; 95% CI: 1.160-1.779; P = 0.001), and high triglyceride (OR: 1.865; 95% CI: 1.446-2.404; p < 0.001). In multinomial logistic regression for 3-level Vit D status analysis, similar trend was found among participants with Vit D insufficiency. Insulin resistance increased in 2.31 and 1.71-folds in Vit D deficiency and insufficiency groups. Besides, association between Vit D deficiency and osteopenia was found only in women. In conclusion, Vit D deficiency was more common in women, and associated with poorer musculoskeletal health and higher cardiovascular and metabolic risk, including higher BMI, DBP, insulin resistance, total cholesterol, and triglyceride." @default.
• W2907720121 created "2019-01-11" @default.
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• W2907720121 date "2018-12-01" @default.
• W2907720121 modified "2023-09-25" @default.
• W2907720121 title "Associations between vitamin D deficiency, musculoskeletal health, and cardiometabolic risk among community-living people in Taiwan" @default.
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• W2907720121 doi "https://doi.org/10.1097/md.0000000000013886" @default.
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