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- W2907730329 abstract "In knee osteoarthritis (OA) patients, a focal cartilage defect is commonly found, especially in the medial compartment. In addition, cartilage softening is often observed at the defect rim. Both factors may alter the loading distribution and thereby the contact pressures, previously related to cartilage degeneration. To determine contact pressure in-vivo during motion, computational modelling can be used. The aim of this study was to analyse knee cartilage pressures during walking in healthy and damaged cartilage using a multi-scale modelling approach. Using 3D motion capture and musculoskeletal models, multi-body simulations of the stance phase of gait calculated knee kinematics and muscle, ligament and contact forces. These were subsequently imposed to a finite element (FE) model including tibial and femoral bones and cartilage. FE analyses were performed using intact cartilage as well as including a medial tibial cartilage defect, with and without softening of the defect rim. Specifically during loadin..." @default.
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- W2907730329 date "2018-11-19" @default.
- W2907730329 modified "2023-09-23" @default.
- W2907730329 title "CARTILAGE CONTACT PRESSURE IN THE KNEE IN THE PRESENCE OF A FOCAL DEFECT" @default.
- W2907730329 hasPublicationYear "2018" @default.
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