FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2907777219> ?p ?o ?g. }

• W2907777219 endingPage "367" @default.
• W2907777219 startingPage "359" @default.
• W2907777219 abstract "What is the central question of this study? What is the relationship between the level of systemic hypercapnia and the magnitude of the additional hyperpnoea produced in response to a standardized level of muscle metaboreflex activation? What is the main finding and its importance? When a standardized activation of the muscle metaboreflex was combined with exposure to increasing levels of hypercapnia, the hyperpnoea this caused increased linearly. The concept of a synergistic interaction between the muscle metaboreflex and the central chemoreflex in humans is supported by this finding.Ventilation increases during muscle metaboreflex activation when postexercise circulatory occlusion (PECO) traps metabolites in resting human muscle, but only in conditions of concurrent systemic hypercapnia. We hypothesize that a linear relationship exists between the level of hypercapnia and the magnitude of the additional hyperpnoea produced in response to a standardized level of muscle metaboreflex activation. Fifteen male subjects performed four trials, in which the end-tidal partial pressure of carbon dioxide ( PET,CO2 ) was elevated by 1, 3, 7 or 10 mmHg above resting values using a dynamic end-tidal forcing system. In each trial, subjects were seated in an isometric dynamometer designed to measure ankle plantar flexor force. Rest for 2 min in room air was followed by 15 min of exposure to one of the four levels of hypercapnia, at which 5 min further rest was followed by 2 min of sustained isometric calf muscle contraction at 50% of predetermined maximal voluntary strength. Immediately before cessation of exercise, a cuff around the upper leg was inflated to a suprasystolic pressure to cause PECO for 3 min, before its deflation and a further 5 min of rest, concluding exposure to hypercapnia. The PECO consistently elevated mean arterial blood pressure by ∼10 mmHg in all trials, indicating similar levels of metaboreflex activation. Increased ventilation during PECO was related to PET,CO2 as described by the following linear regression equation: Change in minute ventilation (l min-1 ) = 0.85 × PET,CO2 (mmHg) + 0.80 (l min-1 ). This finding supports our hypothesis and furthers the idea of a synergistic interaction between muscle metaboreflex activation and central chemoreflex stimulation." @default.
• W2907777219 created "2019-01-11" @default.
• W2907777219 creator A5002267347 @default.
• W2907777219 creator A5017049205 @default.
• W2907777219 creator A5025628380 @default.
• W2907777219 creator A5055683372 @default.
• W2907777219 date "2019-02-03" @default.
• W2907777219 modified "2023-10-10" @default.
• W2907777219 title "Sensitivity of the human ventilatory response to muscle metaboreflex activation during concurrent mild hypercapnia" @default.
• W2907777219 cites W101511518 @default.
• W2907777219 cites W1494236935 @default.
• W2907777219 cites W1522771410 @default.
• W2907777219 cites W1523000871 @default.
• W2907777219 cites W1526545443 @default.
• W2907777219 cites W1552353891 @default.
• W2907777219 cites W1572861945 @default.
• W2907777219 cites W1590983328 @default.
• W2907777219 cites W1756676655 @default.
• W2907777219 cites W1862143633 @default.
• W2907777219 cites W1868015982 @default.
• W2907777219 cites W1910820768 @default.
• W2907777219 cites W1914761702 @default.
• W2907777219 cites W1965036294 @default.
• W2907777219 cites W1976296963 @default.
• W2907777219 cites W1988502279 @default.
• W2907777219 cites W2000481216 @default.
• W2907777219 cites W2034721936 @default.
• W2907777219 cites W2038756689 @default.
• W2907777219 cites W2049972637 @default.
• W2907777219 cites W2056453954 @default.
• W2907777219 cites W2060655597 @default.
• W2907777219 cites W2063260048 @default.
• W2907777219 cites W2079512683 @default.
• W2907777219 cites W2083773011 @default.
• W2907777219 cites W2099995579 @default.
• W2907777219 cites W2111900425 @default.
• W2907777219 cites W2127767982 @default.
• W2907777219 cites W2128675604 @default.
• W2907777219 cites W2128849426 @default.
• W2907777219 cites W2134950977 @default.
• W2907777219 cites W2149351899 @default.
• W2907777219 cites W2149916881 @default.
• W2907777219 cites W2150197223 @default.
• W2907777219 cites W2206938494 @default.
• W2907777219 cites W2394234281 @default.
• W2907777219 cites W2422098695 @default.
• W2907777219 cites W1972331658 @default.
• W2907777219 doi "https://doi.org/10.1113/ep087224" @default.
• W2907777219 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30588681" @default.
• W2907777219 hasPublicationYear "2019" @default.
• W2907777219 type Work @default.
• W2907777219 sameAs 2907777219 @default.
• W2907777219 citedByCount "7" @default.
• W2907777219 countsByYear W29077772192019 @default.
• W2907777219 countsByYear W29077772192020 @default.
• W2907777219 countsByYear W29077772192021 @default.
• W2907777219 countsByYear W29077772192023 @default.
• W2907777219 crossrefType "journal-article" @default.
• W2907777219 hasAuthorship W2907777219A5002267347 @default.
• W2907777219 hasAuthorship W2907777219A5017049205 @default.
• W2907777219 hasAuthorship W2907777219A5025628380 @default.
• W2907777219 hasAuthorship W2907777219A5055683372 @default.
• W2907777219 hasBestOaLocation W29077772191 @default.
• W2907777219 hasConcept C103486182 @default.
• W2907777219 hasConcept C126322002 @default.
• W2907777219 hasConcept C127413603 @default.
• W2907777219 hasConcept C141071460 @default.
• W2907777219 hasConcept C164705383 @default.
• W2907777219 hasConcept C200457457 @default.
• W2907777219 hasConcept C2777037550 @default.
• W2907777219 hasConcept C2780017030 @default.
• W2907777219 hasConcept C42219234 @default.
• W2907777219 hasConcept C534529494 @default.
• W2907777219 hasConcept C71924100 @default.
• W2907777219 hasConcept C78519656 @default.
• W2907777219 hasConcept C79959777 @default.
• W2907777219 hasConceptScore W2907777219C103486182 @default.
• W2907777219 hasConceptScore W2907777219C126322002 @default.
• W2907777219 hasConceptScore W2907777219C127413603 @default.
• W2907777219 hasConceptScore W2907777219C141071460 @default.
• W2907777219 hasConceptScore W2907777219C164705383 @default.
• W2907777219 hasConceptScore W2907777219C200457457 @default.
• W2907777219 hasConceptScore W2907777219C2777037550 @default.
• W2907777219 hasConceptScore W2907777219C2780017030 @default.
• W2907777219 hasConceptScore W2907777219C42219234 @default.
• W2907777219 hasConceptScore W2907777219C534529494 @default.
• W2907777219 hasConceptScore W2907777219C71924100 @default.
• W2907777219 hasConceptScore W2907777219C78519656 @default.
• W2907777219 hasConceptScore W2907777219C79959777 @default.
• W2907777219 hasIssue "3" @default.
• W2907777219 hasLocation W29077772191 @default.
• W2907777219 hasLocation W29077772192 @default.
• W2907777219 hasLocation W29077772193 @default.
• W2907777219 hasLocation W29077772194 @default.
• W2907777219 hasOpenAccess W2907777219 @default.
• W2907777219 hasPrimaryLocation W29077772191 @default.
• W2907777219 hasRelatedWork W1974174011 @default.
• W2907777219 hasRelatedWork W2022939438 @default.

• next