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• W2907948285 endingPage "2013" @default.
• W2907948285 startingPage "2008" @default.
• W2907948285 abstract "Salmonella enterica serovar Typhimurium (S. Typhimurium) is a primary avian pathogen responsible for severe intestinal pathology in younger chickens and economic losses to poultry industry. Furthermore, S. Typhimurium is also able to cause infection in humans, characterized by acute gastrointestinal disease. A study was conducted to investigate antibody response and expression kinetics of interferon gamma (IFNγ), interleukin (IL-12, and IL-18) genes in broiler chicken at 0, 1, 3, 5, 7, 9, 11, 13, and 15 D post infection following experimental infection of S. Typhimurium. Immunological studies showed higher titres of IgG and IgM in the infected group as compared to the age-matched un-infected control group. The Real-Time PCR-based gene expression analysis revealed significant increase of IFNγ, IL-12, and IL-18 mRNA levels in the infected group as compared to their respective controls (P < 0.05). The present study shall help in understanding the immune responses in birds, thus allowing development of more effective vaccines and vaccination strategies." @default.
• W2907948285 created "2019-01-11" @default.
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• W2907948285 date "2019-05-01" @default.
• W2907948285 modified "2023-10-14" @default.
• W2907948285 title "Gene expression and antibody response in chicken against Salmonella Typhimurium challenge" @default.
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• W2907948285 doi "https://doi.org/10.3382/ps/pey560" @default.
• W2907948285 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30597054" @default.
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