Matches in SemOpenAlex for { <https://semopenalex.org/work/W2907983957> ?p ?o ?g. }
- W2907983957 endingPage "264" @default.
- W2907983957 startingPage "256" @default.
- W2907983957 abstract "In this work, we developed and optimized conjugates of carbon-coated iron nanoparticles ([email protected]) with streptavidin and monoclonal antibodies. The conjugation procedure included two stages. First, amino groups were grafted onto the carbon shell to facilitate noncovalent sorption of bovine serum albumin (BSA). Further, the covalent attachment of proteins to the BSA layer via glutaraldehyde coupling was performed. It was established and confirmed that the synthesis procedure is reproducible and allows preparation of stable conjugates. The resulting nanoparticles are clusters of [email protected] particles coated by proteins. The size of the clusters is in the range of 100–190 nm and can be controlled via the tuning of conjugation conditions, including pH, [email protected] ratio, etc. Conjugates of [email protected] with streptavidin and monoclonal antibodies (sizes of approximately 140–150 nm) were synthesized. Proton T2 relaxometry was used to detect these conjugates with very high sensitivity due to the magnetic markers, [email protected] The relaxivity (r2) of different conjugates varied within the range of 290–450 1/s*mM. Conjugate applicability for relaxometry-based assay was confirmed by direct detection of streptococcal protein G and biotinylated BSA in a dot immunoassay." @default.
- W2907983957 created "2019-01-11" @default.
- W2907983957 creator A5002069147 @default.
- W2907983957 creator A5005843490 @default.
- W2907983957 creator A5013901341 @default.
- W2907983957 creator A5013909653 @default.
- W2907983957 creator A5031810213 @default.
- W2907983957 creator A5054634514 @default.
- W2907983957 creator A5057779437 @default.
- W2907983957 creator A5059378512 @default.
- W2907983957 creator A5070570723 @default.
- W2907983957 creator A5073644363 @default.
- W2907983957 creator A5085538565 @default.
- W2907983957 date "2019-04-01" @default.
- W2907983957 modified "2023-10-14" @default.
- W2907983957 title "Conjugation of carbon coated-iron nanoparticles with biomolecules for NMR-based assay" @default.
- W2907983957 cites W1832986645 @default.
- W2907983957 cites W1965699049 @default.
- W2907983957 cites W1968023303 @default.
- W2907983957 cites W1985409438 @default.
- W2907983957 cites W1988051186 @default.
- W2907983957 cites W1998058975 @default.
- W2907983957 cites W2005518649 @default.
- W2907983957 cites W2008438125 @default.
- W2907983957 cites W2009082905 @default.
- W2907983957 cites W2012659668 @default.
- W2907983957 cites W2015773403 @default.
- W2907983957 cites W2017562442 @default.
- W2907983957 cites W2018173850 @default.
- W2907983957 cites W2018648183 @default.
- W2907983957 cites W2031045812 @default.
- W2907983957 cites W2037846869 @default.
- W2907983957 cites W2053121035 @default.
- W2907983957 cites W2084186494 @default.
- W2907983957 cites W2085134679 @default.
- W2907983957 cites W2094978364 @default.
- W2907983957 cites W2118817262 @default.
- W2907983957 cites W2126916701 @default.
- W2907983957 cites W2144843667 @default.
- W2907983957 cites W2156300745 @default.
- W2907983957 cites W2273379195 @default.
- W2907983957 cites W2288313733 @default.
- W2907983957 cites W2291336353 @default.
- W2907983957 cites W2299249863 @default.
- W2907983957 cites W2301545249 @default.
- W2907983957 cites W2315618025 @default.
- W2907983957 cites W2321097270 @default.
- W2907983957 cites W2413990019 @default.
- W2907983957 cites W2509226461 @default.
- W2907983957 cites W2565428704 @default.
- W2907983957 cites W2588710386 @default.
- W2907983957 cites W2610704621 @default.
- W2907983957 cites W2614941555 @default.
- W2907983957 cites W2768398825 @default.
- W2907983957 cites W2800910389 @default.
- W2907983957 cites W2802294329 @default.
- W2907983957 doi "https://doi.org/10.1016/j.colsurfb.2019.01.009" @default.
- W2907983957 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30623813" @default.
- W2907983957 hasPublicationYear "2019" @default.
- W2907983957 type Work @default.
- W2907983957 sameAs 2907983957 @default.
- W2907983957 citedByCount "19" @default.
- W2907983957 countsByYear W29079839572019 @default.
- W2907983957 countsByYear W29079839572020 @default.
- W2907983957 countsByYear W29079839572021 @default.
- W2907983957 countsByYear W29079839572022 @default.
- W2907983957 countsByYear W29079839572023 @default.
- W2907983957 crossrefType "journal-article" @default.
- W2907983957 hasAuthorship W2907983957A5002069147 @default.
- W2907983957 hasAuthorship W2907983957A5005843490 @default.
- W2907983957 hasAuthorship W2907983957A5013901341 @default.
- W2907983957 hasAuthorship W2907983957A5013909653 @default.
- W2907983957 hasAuthorship W2907983957A5031810213 @default.
- W2907983957 hasAuthorship W2907983957A5054634514 @default.
- W2907983957 hasAuthorship W2907983957A5057779437 @default.
- W2907983957 hasAuthorship W2907983957A5059378512 @default.
- W2907983957 hasAuthorship W2907983957A5070570723 @default.
- W2907983957 hasAuthorship W2907983957A5073644363 @default.
- W2907983957 hasAuthorship W2907983957A5085538565 @default.
- W2907983957 hasConcept C134306372 @default.
- W2907983957 hasConcept C155672457 @default.
- W2907983957 hasConcept C159654299 @default.
- W2907983957 hasConcept C171250308 @default.
- W2907983957 hasConcept C178790620 @default.
- W2907983957 hasConcept C180577832 @default.
- W2907983957 hasConcept C185592680 @default.
- W2907983957 hasConcept C192562407 @default.
- W2907983957 hasConcept C197336794 @default.
- W2907983957 hasConcept C203014093 @default.
- W2907983957 hasConcept C204628709 @default.
- W2907983957 hasConcept C21951064 @default.
- W2907983957 hasConcept C23963754 @default.
- W2907983957 hasConcept C2776190903 @default.
- W2907983957 hasConcept C2777529624 @default.
- W2907983957 hasConcept C2778204606 @default.
- W2907983957 hasConcept C2778889443 @default.
- W2907983957 hasConcept C2780420688 @default.
- W2907983957 hasConcept C33923547 @default.