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- W2908703656 abstract "Novel inhibitors of the newly discovered herbicide target enzyme imidazole glycerol phosphate dehydratase are described. The most potent inhibitor, compound 6 (IC50 < 1 μM), arose by linking a 1,2,4-triazole and phosphonic acid via a five atom chain. The use of malonate as a phosphate equivalent also gave rise to inhibitors, the best being compound 12 (IC50 ∼ 6μM)." @default.
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- W2908703656 date "1996-03-01" @default.
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- W2908703656 title "Synthesis of inhibitors of imidazole glycerol phosphate dehydratase" @default.
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- W2908703656 doi "https://doi.org/10.1016/0960-894x(96)00076-5" @default.
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