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- W2908916323 abstract "White spot syndrome virus (WSSV) is the most devastating DNA virus that causes shrimp mortality worldwide. To better understand WSSV and Penaeus monodon interactions, WSSV-encoded microRNAs (wsv-miRs) were identified by small RNA cloning and next-generation sequencing. Ten wsv-miRs were identified and their expressions can be detected in WSSV-infected tissues only. These wsv-miRs and their flanking sequences can spontaneously form hairpin structure as predicted by Mfold. The expression profiles of 6 wsv-miRs increased dependent on time course of WSSV infection and slightly decreased after 48 hours WSSV challenge. The highest expression was wsv-miR-9 followed by miR-13 and -15. Computational prediction of the candidate targets of wsv-miRs revealed possible functions of wsv-miRs in the controlling of apoptosis, transcription and signaling. This finding provided insights into WSSV-host interaction." @default.
- W2908916323 created "2019-01-25" @default.
- W2908916323 creator A5036381505 @default.
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- W2908916323 date "2019-03-01" @default.
- W2908916323 modified "2023-10-15" @default.
- W2908916323 title "Identification and expression of white spot syndrome virus-encoded microRNAs in infected Penaeus monodon" @default.
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- W2908916323 doi "https://doi.org/10.1016/j.aquaculture.2019.01.023" @default.
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