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• W2908955228 abstract "Dp71 is the major form of dystrophins (Dp) in the supraoptic nucleus (SON) and in the neural lobe of hypophysis (NL/HP). Dp71-null mice exhibit a hypo-osmolar status attributed to an altered osmosensitivity of the SON and to a perturbed vasopressinergic axis. Because oxytocin (OT) is implicated in osmoregulation via natriuresis, this study explored the oxytocinergic axis in Dp71-null mice after salt-loading (SL). Under normosmolar conditions, OT-mRNA expression was higher in the Dp71-null SON compared to wild-type (wt) and the OT peptide level has not changed. Dp-immunostaining was localized in astrocytes end-feet surrounding vessels in wt SON. This distribution changed in Dp71-null SON, Dp being detected in OT-soma of MCNs. nNOS and NADPH-diaphorase levels increased in the OT area of the Dp71-null SON compared to wt. In the NL/HP, OT level reduced in Dp71-null mice and Dp localization changed from pituicytes end-feet in wt SON to OT terminals in Dp71-null SON. Salt-Loading resulted in an increase of OT-mRNA and peptide levels in wt SON but had no effect in Dp71-null SON. In the NL/HP, OT content was reduced after SL. For Dp71-null mice, OT level, already low in control, was not modified by SL. Dp level was not affected by SL in the SON nor in the NL/HP. Our data confirmed the importance of Dp71 for the SON functionality in osmoregulation. The localization of Dp71 at the glial-vascular interface could be associated with SON osmosensitivity, leading to an adequate OT synthesis in the SON and release from the NL/HP upon plasmatic hyperosmolality." @default.
• W2908955228 created "2019-01-25" @default.
• W2908955228 creator A5033949947 @default.
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• W2908955228 date "2019-04-01" @default.
• W2908955228 modified "2023-09-30" @default.
• W2908955228 title "Effect of Dp71 deficiency on the oxytocin hypothalamic axis in osmoregulation function in mice" @default.
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• W2908955228 cites W1968635761 @default.
• W2908955228 cites W1970678693 @default.
• W2908955228 cites W1971143219 @default.
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• W2908955228 doi "https://doi.org/10.1016/j.acthis.2019.01.002" @default.
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• W2908955228 hasPublicationYear "2019" @default.
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