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- W2908996693 abstract "Insulin resistance is a pathophysiological state defined by impaired responses to insulin and is a risk factor for several metabolic diseases, most notably type 2 diabetes. Insulin resistance occurs in insulin target tissues including liver, adipose and skeletal muscle. Methods such as insulin tolerance tests and hyperinsulinaemic-euglycaemic clamps permit assessment of insulin responses in specific tissues and allow the study of the progression and causes of insulin resistance. Here we detail a protocol for assessing insulin action in adipose and muscle tissues in anesthetized mice administered with insulin intravenously." @default.
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- W2908996693 date "2019-01-01" @default.
- W2908996693 modified "2023-10-16" @default.
- W2908996693 title "Insulin Tolerance Test under Anaesthesia to Measure Tissue-specific Insulin-stimulated Glucose Disposal" @default.
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- W2908996693 doi "https://doi.org/10.21769/bioprotoc.3146" @default.
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