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- W2909162567 abstract "CoQ 10 is a fat-soluble vitamin-quinone found in most cells and membranes. Ubiquinone is an obligatory component of the respiratory chain in the inner mitochondrial membrane coupled to ATP synthesis and an antioxidant. Its additional localization in different subcellular fractions is probably associated with its multiple functions in the cell. Ubiquinone can influence on activity of many enzymes with different functions (antioxidant, energy, etc). CoQ 10 is also a cofactor in the reaction catalyzed by the mitochondrial protein dihydroorotate dehydrogenase and uncoupling proteins UCPs. One of the functions of ubiquinon is gene expression regulation. He is involved in inflammatory processes and lipid metabolism via gene expression. Furthermore, CoQ 10 can influence on epigenetic modifications that able to determine the gene expression (DNA methylation, miRNA, histone modifications). Ubiquinone is the introduction of metabolic drugs and may be recommended for the prevention and treatment of metabolic disorders caused by various pathological conditions." @default.
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- W2909162567 date "2017-02-01" @default.
- W2909162567 modified "2023-09-25" @default.
- W2909162567 title "MODERN ASPECTS OF UBIQUINONE FUNCTIONS IN CELL METABOLISM" @default.
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- W2909162567 doi "https://doi.org/10.30970/vlubs.2017.75.01" @default.
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