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• W2909409778 abstract "Abstract Motivation Promoters are short DNA consensus sequences that are localized proximal to the transcription start sites of genes, allowing transcription initiation of particular genes. However, the precise prediction of promoters remains a challenging task because individual promoters often differ from the consensus at one or more positions. Results In this study, we present a new multi-layer computational approach, called MULTiPly, for recognizing promoters and their specific types. MULTiPly took into account the sequences themselves, including both local information such as k-tuple nucleotide composition, dinucleotide-based auto covariance and global information of the entire samples based on bi-profile Bayes and k-nearest neighbour feature encodings. Specifically, the F-score feature selection method was applied to identify the best unique type of feature prediction results, in combination with other types of features that were subsequently added to further improve the prediction performance of MULTiPly. Benchmarking experiments on the benchmark dataset and comparisons with five state-of-the-art tools show that MULTiPly can achieve a better prediction performance on 5-fold cross-validation and jackknife tests. Moreover, the superiority of MULTiPly was also validated on a newly constructed independent test dataset. MULTiPly is expected to be used as a useful tool that will facilitate the discovery of both general and specific types of promoters in the post-genomic era. Availability and implementation The MULTiPly webserver and curated datasets are freely available at http://flagshipnt.erc.monash.edu/MULTiPly/. Supplementary information Supplementary data are available at Bioinformatics online." @default.
• W2909409778 created "2019-01-25" @default.
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• W2909409778 date "2019-01-11" @default.
• W2909409778 modified "2023-10-17" @default.
• W2909409778 title "MULTiPly: a novel multi-layer predictor for discovering general and specific types of promoters" @default.
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• W2909409778 cites W1906342810 @default.
• W2909409778 cites W1943237984 @default.
• W2909409778 cites W1964497435 @default.
• W2909409778 cites W1973310562 @default.
• W2909409778 cites W1978643997 @default.
• W2909409778 cites W1991141438 @default.
• W2909409778 cites W1996774362 @default.
• W2909409778 cites W2001349696 @default.
• W2909409778 cites W2021823827 @default.
• W2909409778 cites W2034070267 @default.
• W2909409778 cites W2037611385 @default.
• W2909409778 cites W2048356293 @default.
• W2909409778 cites W2052892694 @default.
• W2909409778 cites W2080748087 @default.
• W2909409778 cites W2088117005 @default.
• W2909409778 cites W2093080369 @default.
• W2909409778 cites W2093897670 @default.
• W2909409778 cites W2100805904 @default.
• W2909409778 cites W2101492309 @default.
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• W2909409778 cites W2117357746 @default.
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• W2909409778 cites W2120026469 @default.
• W2909409778 cites W2121184378 @default.
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• W2909409778 cites W2124266758 @default.
• W2909409778 cites W2152339342 @default.
• W2909409778 cites W2152365098 @default.
• W2909409778 cites W2152705149 @default.
• W2909409778 cites W2153635508 @default.
• W2909409778 cites W2160165249 @default.
• W2909409778 cites W2168012258 @default.
• W2909409778 cites W2237040395 @default.
• W2909409778 cites W2281326002 @default.
• W2909409778 cites W2313411748 @default.
• W2909409778 cites W2400814742 @default.
• W2909409778 cites W2462807123 @default.
• W2909409778 cites W2526763554 @default.
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• W2909409778 cites W2737592062 @default.
• W2909409778 cites W2749697459 @default.
• W2909409778 cites W2751166719 @default.
• W2909409778 cites W2754289562 @default.
• W2909409778 cites W2766389776 @default.
• W2909409778 cites W2768705872 @default.
• W2909409778 cites W2792363117 @default.
• W2909409778 cites W2793168264 @default.
• W2909409778 cites W2794797435 @default.
• W2909409778 cites W2799200068 @default.
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• W2909409778 doi "https://doi.org/10.1093/bioinformatics/btz016" @default.
• W2909409778 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6736106" @default.
• W2909409778 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30649179" @default.
• W2909409778 hasPublicationYear "2019" @default.
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