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• W2909968342 abstract "Background Systemic sclerosis (SSc) is a very heterogeneous multisystem connective tissue disease. The majority of affected patients develop initial clinical symptoms between the age of 30 to 50 years. It is not known whether an ageing population affects the clinical phenotype of SSc. Objectives To investigate the relationship of the age at disease onset and clinical characteristics in SSc patients using the registry of the German Network for Systemic Scleroderma. Methods Clinical data of the patient registry, currently including 4021 patients, were evaluated. Three age ranges at disease onset ( 60 years) were correlated with clinical characteristics. Results Among all SSc patients, 27% of patients developed first non-raynaud symptoms at the age 60 years developed significantly (p Conclusions In this registry, nearly one third of patients developed SSc at an age above 60 years. These are mostly of the limited cutanous subtype with frequent PH. These findings have an important influence on recommendations on diagnosis and theray of SSC. Disclosure of Interest None declared" @default.
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• W2909968342 date "2018-06-01" @default.
• W2909968342 modified "2023-10-01" @default.
• W2909968342 title "SAT0506 Ssc in older age: frequent and with a different phenotype. data of the german network for systemic sclerosis" @default.
• W2909968342 doi "https://doi.org/10.1136/annrheumdis-2018-eular.5214" @default.
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