FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2910029369> ?p ?o ?g. }

• W2910029369 abstract "Dementia is a chronic condition which progressively affects memory and other cognitive functions, social behaviour, and ability to carry out daily activities. To date, no treatment is clearly effective in preventing progression of the disease, and most treatments are symptomatic, often aiming to improve people's psychological symptoms or behaviours which are challenging for carers. A range of new therapeutic strategies has been evaluated in research, and the use of trained animals in therapy sessions, termed animal-assisted therapy (AAT), is receiving increasing attention.To evaluate the efficacy and safety of animal-assisted therapy for people with dementia.We searched ALOIS: the Cochrane Dementia and Cognitive Improvement Group's Specialised Register on 5 September 2019. ALOIS contains records of clinical trials identified from monthly searches of major healthcare databases, trial registries, and grey literature sources. We also searched MEDLINE (OvidSP), Embase (OvidSP), PsycINFO (OvidSP), CINAHL (EBSCOhost), ISI Web of Science, ClinicalTrials.gov, and the WHO's trial registry portal.We included randomised controlled trials (RCTs), cluster-randomised trials, and randomised cross-over trials that compared AAT versus no AAT, AAT using live animals versus alternatives such as robots or toys, or AAT versus any other active intervention.We extracted data using the standard methods of Cochrane Dementia. Two review authors independently assessed the eligibility and risk of bias of the retrieved records. We expressed our results using mean difference (MD), standardised mean difference (SMD), and risk ratio (RR) with their 95% confidence intervals (CIs) where appropriate.We included nine RCTs from 10 reports. All nine studies were conducted in Europe and the US. Six studies were parallel-group, individually randomised RCTs; one was a randomised cross-over trial; and two were cluster-RCTs that were possibly related where randomisation took place at the level of the day care and nursing home. We identified two ongoing trials from trial registries. There were three comparisons: AAT versus no AAT (standard care or various non-animal-related activities), AAT using live animals versus robotic animals, and AAT using live animals versus the use of a soft animal toy. The studies evaluated 305 participants with dementia. One study used horses and the remainder used dogs as the therapy animal. The duration of the intervention ranged from six weeks to six months, and the therapy sessions lasted between 10 and 90 minutes each, with a frequency ranging from one session every two weeks to two sessions per week. There was a wide variety of instruments used to measure the outcomes. All studies were at high risk of performance bias and unclear risk of selection bias. Our certainty about the results for all major outcomes was very low to moderate. Comparing AAT versus no AAT, participants who received AAT may be slightly less depressed after the intervention (MD -2.87, 95% CI -5.24 to -0.50; 2 studies, 83 participants; low-certainty evidence), but they did not appear to have improved quality of life (MD 0.45, 95% CI -1.28 to 2.18; 3 studies, 164 participants; moderate-certainty evidence). There were no clear differences in all other major outcomes, including social functioning (MD -0.40, 95% CI -3.41 to 2.61; 1 study, 58 participants; low-certainty evidence), problematic behaviour (SMD -0.34, 95% CI -0.98 to 0.30; 3 studies, 142 participants; very-low-certainty evidence), agitation (SMD -0.39, 95% CI -0.89 to 0.10; 3 studies, 143 participants; very-low-certainty evidence), activities of daily living (MD 4.65, 95% CI -16.05 to 25.35; 1 study, 37 participants; low-certainty evidence), and self-care ability (MD 2.20, 95% CI -1.23 to 5.63; 1 study, 58 participants; low-certainty evidence). There were no data on adverse events. Comparing AAT using live animals versus robotic animals, one study (68 participants) found mixed effects on social function, with longer duration of physical contact but shorter duration of talking in participants who received AAT using live animals versus robotic animals (median: 93 seconds with live versus 28 seconds with robotic for physical contact; 164 seconds with live versus 206 seconds with robotic for talk directed at a person; 263 seconds with live versus 307 seconds with robotic for talk in total). Another study showed no clear differences between groups in behaviour measured using the Neuropsychiatric Inventory (MD -6.96, 95% CI -14.58 to 0.66; 78 participants; low-certainty evidence) or quality of life (MD -2.42, 95% CI -5.71 to 0.87; 78 participants; low-certainty evidence). There were no data on the other outcomes. Comparing AAT using live animals versus a soft toy cat, one study (64 participants) evaluated only social functioning, in the form of duration of contact and talking. The data were expressed as median and interquartile ranges. Duration of contact was slightly longer in participants in the AAT group and duration of talking slightly longer in those exposed to the toy cat. This was low-certainty evidence.We found low-certainty evidence that AAT may slightly reduce depressive symptoms in people with dementia. We found no clear evidence that AAT affects other outcomes in this population, with our certainty in the evidence ranging from very-low to moderate depending on the outcome. We found no evidence on safety or effects on the animals. Therefore, clear conclusions cannot yet be drawn about the overall benefits and risks of AAT in people with dementia. Further well-conducted RCTs are needed to improve the certainty of the evidence. In view of the difficulty in achieving blinding of participants and personnel in such trials, future RCTs should work on blinding outcome assessors, document allocation methods clearly, and include major patient-important outcomes such as affect, emotional and social functioning, quality of life, adverse events, and outcomes for animals." @default.
• W2910029369 created "2019-01-25" @default.
• W2910029369 creator A5010672288 @default.
• W2910029369 creator A5013349830 @default.
• W2910029369 creator A5052318923 @default.
• W2910029369 creator A5070240930 @default.
• W2910029369 creator A5072236267 @default.
• W2910029369 creator A5074865748 @default.
• W2910029369 date "2019-11-25" @default.
• W2910029369 modified "2023-09-27" @default.
• W2910029369 title "Animal-assisted therapy for dementia" @default.
• W2910029369 cites W1164896577 @default.
• W2910029369 cites W1534461621 @default.
• W2910029369 cites W1807810766 @default.
• W2910029369 cites W1847168837 @default.
• W2910029369 cites W1854493230 @default.
• W2910029369 cites W1941651868 @default.
• W2910029369 cites W1953027527 @default.
• W2910029369 cites W1958671952 @default.
• W2910029369 cites W1960936936 @default.
• W2910029369 cites W1970501084 @default.
• W2910029369 cites W1970711565 @default.
• W2910029369 cites W1971150621 @default.
• W2910029369 cites W1971351343 @default.
• W2910029369 cites W1985844197 @default.
• W2910029369 cites W1988108022 @default.
• W2910029369 cites W1991517279 @default.
• W2910029369 cites W1999777934 @default.
• W2910029369 cites W2003392255 @default.
• W2910029369 cites W2005364279 @default.
• W2910029369 cites W2008854521 @default.
• W2910029369 cites W2016405877 @default.
• W2910029369 cites W2017733654 @default.
• W2910029369 cites W2032123050 @default.
• W2910029369 cites W2032488741 @default.
• W2910029369 cites W2039547944 @default.
• W2910029369 cites W2040686586 @default.
• W2910029369 cites W2044730241 @default.
• W2910029369 cites W2044778685 @default.
• W2910029369 cites W2045722992 @default.
• W2910029369 cites W2058161128 @default.
• W2910029369 cites W2058275889 @default.
• W2910029369 cites W2059992362 @default.
• W2910029369 cites W2060943766 @default.
• W2910029369 cites W2064151239 @default.
• W2910029369 cites W2068015182 @default.
• W2910029369 cites W2070585888 @default.
• W2910029369 cites W2074960413 @default.
• W2910029369 cites W2081680598 @default.
• W2910029369 cites W2084114496 @default.
• W2910029369 cites W2095494096 @default.
• W2910029369 cites W2096847786 @default.
• W2910029369 cites W2099193270 @default.
• W2910029369 cites W2111963393 @default.
• W2910029369 cites W2112150247 @default.
• W2910029369 cites W2112249672 @default.
• W2910029369 cites W2112519660 @default.
• W2910029369 cites W2115017507 @default.
• W2910029369 cites W2125090342 @default.
• W2910029369 cites W2128529067 @default.
• W2910029369 cites W2132842417 @default.
• W2910029369 cites W2134857549 @default.
• W2910029369 cites W2135100269 @default.
• W2910029369 cites W2148080316 @default.
• W2910029369 cites W2157823046 @default.
• W2910029369 cites W2163017976 @default.
• W2910029369 cites W2165086835 @default.
• W2910029369 cites W2166924983 @default.
• W2910029369 cites W2167311298 @default.
• W2910029369 cites W2167373945 @default.
• W2910029369 cites W2171006997 @default.
• W2910029369 cites W2175635532 @default.
• W2910029369 cites W2193764494 @default.
• W2910029369 cites W2225060253 @default.
• W2910029369 cites W2238562952 @default.
• W2910029369 cites W2254114366 @default.
• W2910029369 cites W2294211165 @default.
• W2910029369 cites W2333793022 @default.
• W2910029369 cites W2347101224 @default.
• W2910029369 cites W2412564330 @default.
• W2910029369 cites W2583431242 @default.
• W2910029369 cites W2592383474 @default.
• W2910029369 cites W2601162258 @default.
• W2910029369 cites W2613103669 @default.
• W2910029369 cites W2616267547 @default.
• W2910029369 cites W2759242243 @default.
• W2910029369 cites W2767097784 @default.
• W2910029369 cites W2773346251 @default.
• W2910029369 cites W2795497323 @default.
• W2910029369 cites W2804250915 @default.
• W2910029369 cites W2807647500 @default.
• W2910029369 cites W2883963136 @default.
• W2910029369 cites W2910029369 @default.
• W2910029369 cites W2912326256 @default.
• W2910029369 cites W2928759593 @default.
• W2910029369 cites W2974747689 @default.
• W2910029369 cites W4210254506 @default.
• W2910029369 cites W4247169983 @default.
• W2910029369 cites W4247665917 @default.
• W2910029369 cites W4301949645 @default.

• next