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- W2910033321 abstract "This chapter addresses the functionalization of sensing surfaces and related activities. Biosensors are used for the analysis of bioanalyte materials such as cell cultures, blood, urine, saliva, food, air, water, soil, and vegetation. Biosensing is categorized as optical, electrochemical, and physical. Functionalization is a significant process in biosensing techniques. Biosensor substrates are functionalized in physical, chemical, and biological methods. They support efficient biomolecular capture, and amplify the signal received from the transducer. Ultimately, this leads to better biosensing. Physical modification of surfaces involves processes such as etching and nanostructuring of surfaces. Chemical functionalization includes adsorption and forming self-assembled monolayers using amines, thiols, silanes, polymers, and nanomaterials. Biological functionalization immobilizes the biorecognition elements such as enzymes, antibodies, and aptamers on sensor substrates. The substrates such as glass, silicon, gold, and electrodes made with different materials are functionalized. Nanomaterials with different morphologies such as nanorods and nanofibers are applied for the surface modification of sensor substrates. Optical responses of metal nanoparticles such as gold and silver nanoparticles have certain roles in functionalization. This chapter reviews the various materials and techniques involved in the functionalization process. The sensitivity and selectivity of the sensors are increased by the functionalization process. Effective functionalization is feasible due to the development of nanomaterials, coating techniques, and novel biorecognition elements. In addition, the reviewed trends reveal the challenges, growth status, scope, and sustainable future of this field." @default.
- W2910033321 created "2019-01-25" @default.
- W2910033321 creator A5072162868 @default.
- W2910033321 date "2019-01-01" @default.
- W2910033321 modified "2023-09-25" @default.
- W2910033321 title "Functionalization on Sensing Surfaces for Efficient Biomolecular Capturing" @default.
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- W2910033321 doi "https://doi.org/10.1016/b978-0-12-813900-4.00003-8" @default.
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