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- W2910050847 abstract "Aim: To perform a review of the literature reporting on randomised controlled trials (RCTs) comparing treatments for faecal incontinence (FI) in adults.Methods: A literature search of MEDLINE, Embase, Science Citation Index Expanded and Cochrane was performed in order to identify RCTs reporting on treatments for FI.Results: The review included 60 RCTs reporting on 4838 patients with a mean age ranging from 36.8 to 88 years. From the included RCTs, 32 did not identify a significant difference between the treatments compared. Contradictory results were identified in RCTs comparing percutaneous posterior tibial nerve stimulation and transcutaneous tibial nerve stimulation versus sham stimulation, biofeedback-pelvic floor muscle training (BF-PFMT) versus PFMT, and between bulking agents such as PTQTM versus Durasphere®. In two separate RCTs, combination treatment of amplitude-modulated medium frequency stimulation and electromyography-biofeedback (EMG-BF), was noted to be superior to EMG-BF and low-frequency electrical stimulation alone. Combination of non-surgical treatments such as BF with sphincteroplasty significantly improved continence scores compared to sphincteroplasty alone. Surgical treatments were associated with higher rates of serious adverse events compared to non-surgical interventions.Conclusions: The current evidence has not identified significant differences between treatments for FI, and where differences were identified, the results were contradictory between RCTs." @default.
- W2910050847 created "2019-01-25" @default.
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- W2910050847 date "2019-01-02" @default.
- W2910050847 modified "2023-09-26" @default.
- W2910050847 title "A systematic review of the literature reporting on randomised controlled trials comparing treatments for faecal incontinence in adults" @default.
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- W2910050847 doi "https://doi.org/10.1080/00015458.2018.1549392" @default.
- W2910050847 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30644337" @default.
- W2910050847 hasPublicationYear "2019" @default.
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