FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2910080429> ?p ?o ?g. }

• W2910080429 abstract "Abstract Purpose The primary objective was to validate the software DoseFX developed by Comecer for organ level dosimetry. Residence times ( τ ) and absorbed doses (D) to organs were compared to the quantities obtained with OLINDA1.1 and VoxelMed2.0 (voxel/organ-level dosimetry software). Methods and materials SPECT/CT sequential dosimetry scans acquired in a PRRT trial were considered. Every patient was scanned 5 times after a therapeutic administration of 177Lu-DOTATOC. Two different clinical studies were performed. Study (A): the same activity values for the organs were used for the calculation of τ and D with DoseFX and OLINDA1.1 in a sample of 25 patients. Study (B): the same activity values for the organs were used with DoseFX and VoxelMed_Organ in a sample of 20 patients, while VoxelMed_Voxel works directly on images. For this study we did not calculate τ with OLINDA1.1, but we used τ calculated with VoxelMed_Organ. The Wilcoxon test was used (p-values in plots). Results The mean percentage differences (PD) between DoseFX and OLINDA1.1 for the study (A) were ( τ ;D): −1.1;−1.3 liver, 0.1;0.1 kidney and −1.3;−1.3 spleen. For the study (B) mean PD between DoseFX and OLINDA1.1 were ( τ ;D): 5.4;4.2 liver, 0.0;2.7 kidney and 4.8;10.0 spleen; between DoseFX and VoxelMed2.0 were ( τ ;D): −0.7;9.8 liver, 0.6;13.8 kidney and 1.4;17.9 spleen. Data distribution in box plots. The study (A) showed a good agreement between DoseFX and OLINDA1.1 both for τ and for D, with mean PD smaller than 1%. In study (B) larger PDs were observed between DoseFX and VoxelMed, making them significantly different. This is most likely due to the different calculation modality of τ and D. Conclusion The main conclusion is that DoseFX is a tool for organ dosimetry as safe as OLINDA1.1 in PRRT. Particular attention should be paid to the differences in the dosimetry calculation techniques implemented in available tools." @default.
• W2910080429 created "2019-01-25" @default.
• W2910080429 creator A5003266494 @default.
• W2910080429 creator A5025787712 @default.
• W2910080429 creator A5026341152 @default.
• W2910080429 creator A5029221944 @default.
• W2910080429 creator A5032411699 @default.
• W2910080429 creator A5039659665 @default.
• W2910080429 creator A5045569134 @default.
• W2910080429 creator A5050573682 @default.
• W2910080429 creator A5082435105 @default.
• W2910080429 date "2018-12-01" @default.
• W2910080429 modified "2023-10-17" @default.
• W2910080429 title "142. DoseFX: A software for dosimetry of organs and lesions in molecular radiotherapy" @default.
• W2910080429 doi "https://doi.org/10.1016/j.ejmp.2018.04.153" @default.
• W2910080429 hasPublicationYear "2018" @default.
• W2910080429 type Work @default.
• W2910080429 sameAs 2910080429 @default.
• W2910080429 citedByCount "0" @default.
• W2910080429 crossrefType "journal-article" @default.
• W2910080429 hasAuthorship W2910080429A5003266494 @default.
• W2910080429 hasAuthorship W2910080429A5025787712 @default.
• W2910080429 hasAuthorship W2910080429A5026341152 @default.
• W2910080429 hasAuthorship W2910080429A5029221944 @default.
• W2910080429 hasAuthorship W2910080429A5032411699 @default.
• W2910080429 hasAuthorship W2910080429A5039659665 @default.
• W2910080429 hasAuthorship W2910080429A5045569134 @default.
• W2910080429 hasAuthorship W2910080429A5050573682 @default.
• W2910080429 hasAuthorship W2910080429A5082435105 @default.
• W2910080429 hasConcept C126322002 @default.
• W2910080429 hasConcept C126838900 @default.
• W2910080429 hasConcept C151337348 @default.
• W2910080429 hasConcept C2780091579 @default.
• W2910080429 hasConcept C2780931953 @default.
• W2910080429 hasConcept C2989005 @default.
• W2910080429 hasConcept C509974204 @default.
• W2910080429 hasConcept C54170458 @default.
• W2910080429 hasConcept C71924100 @default.
• W2910080429 hasConcept C75088862 @default.
• W2910080429 hasConceptScore W2910080429C126322002 @default.
• W2910080429 hasConceptScore W2910080429C126838900 @default.
• W2910080429 hasConceptScore W2910080429C151337348 @default.
• W2910080429 hasConceptScore W2910080429C2780091579 @default.
• W2910080429 hasConceptScore W2910080429C2780931953 @default.
• W2910080429 hasConceptScore W2910080429C2989005 @default.
• W2910080429 hasConceptScore W2910080429C509974204 @default.
• W2910080429 hasConceptScore W2910080429C54170458 @default.
• W2910080429 hasConceptScore W2910080429C71924100 @default.
• W2910080429 hasConceptScore W2910080429C75088862 @default.
• W2910080429 hasLocation W29100804291 @default.
• W2910080429 hasOpenAccess W2910080429 @default.
• W2910080429 hasPrimaryLocation W29100804291 @default.
• W2910080429 hasRelatedWork W1964713829 @default.
• W2910080429 hasRelatedWork W2097226364 @default.
• W2910080429 hasRelatedWork W2099680734 @default.
• W2910080429 hasRelatedWork W2105853795 @default.
• W2910080429 hasRelatedWork W2281170410 @default.
• W2910080429 hasRelatedWork W2417083896 @default.
• W2910080429 hasRelatedWork W2512421757 @default.
• W2910080429 hasRelatedWork W2597998745 @default.
• W2910080429 hasRelatedWork W2910080429 @default.
• W2910080429 hasRelatedWork W2923700792 @default.
• W2910080429 isParatext "false" @default.
• W2910080429 isRetracted "false" @default.
• W2910080429 magId "2910080429" @default.
• W2910080429 workType "article" @default.