Matches in SemOpenAlex for { <https://semopenalex.org/work/W2910080781> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2910080781 abstract "The frequent demand for effective eye therapies is acting as driving force for the development of injectable hydrogels as new medical devices for controlled delivery and filling purposes. The delicate structure and the protective physiological process of our eye exert a defense system against ophthalmic delivery of drug, which ultimately led to poor precorneal drug loss, resulting in poor ocular bioavailability. To improve ophthalmic preparation’s bioavailability, there are valuable efforts directed toward newer drug delivery systems for ophthalmic administration. As we know that other conventional delivery system gives poor therapeutic response and bioavailability because tears have high fluid turnover and dynamics due to which rapid elimination of drug from the eye takes place. In situ polymeric formulations are drug delivery systems that are in sol form before administration in the body, but on administration, they undergo gelation in situ, to form a gel. The formation of gels depends on factors such as temperature modulation, pH change, presence of ions, and ultraviolet irradiation, from which the drug gets released in a sustained and controlled manner. This article introduces the properties and mechanisms of injectable hydrogels and summarizes their versatile application in the treatment of ophthalmic diseases, including age-related macular degeneration, cataracts, diabetic retinopathy, glaucoma, and intraocular cancers." @default.
- W2910080781 created "2019-01-25" @default.
- W2910080781 creator A5027162427 @default.
- W2910080781 creator A5038419314 @default.
- W2910080781 creator A5062112757 @default.
- W2910080781 creator A5062621554 @default.
- W2910080781 date "2018-06-01" @default.
- W2910080781 modified "2023-09-24" @default.
- W2910080781 title "Hydrogels in ophthalmic drug delivery system - A mini review" @default.
- W2910080781 doi "https://doi.org/10.21276/apjhs.2018.5.2.19" @default.
- W2910080781 hasPublicationYear "2018" @default.
- W2910080781 type Work @default.
- W2910080781 sameAs 2910080781 @default.
- W2910080781 citedByCount "3" @default.
- W2910080781 countsByYear W29100807812020 @default.
- W2910080781 countsByYear W29100807812022 @default.
- W2910080781 crossrefType "journal-article" @default.
- W2910080781 hasAuthorship W2910080781A5027162427 @default.
- W2910080781 hasAuthorship W2910080781A5038419314 @default.
- W2910080781 hasAuthorship W2910080781A5062112757 @default.
- W2910080781 hasAuthorship W2910080781A5062621554 @default.
- W2910080781 hasBestOaLocation W29100807811 @default.
- W2910080781 hasConcept C108586683 @default.
- W2910080781 hasConcept C118487528 @default.
- W2910080781 hasConcept C163588942 @default.
- W2910080781 hasConcept C171250308 @default.
- W2910080781 hasConcept C178790620 @default.
- W2910080781 hasConcept C181389837 @default.
- W2910080781 hasConcept C185592680 @default.
- W2910080781 hasConcept C192562407 @default.
- W2910080781 hasConcept C2779820397 @default.
- W2910080781 hasConcept C2780035454 @default.
- W2910080781 hasConcept C2780225610 @default.
- W2910080781 hasConcept C2983812674 @default.
- W2910080781 hasConcept C71924100 @default.
- W2910080781 hasConcept C98274493 @default.
- W2910080781 hasConceptScore W2910080781C108586683 @default.
- W2910080781 hasConceptScore W2910080781C118487528 @default.
- W2910080781 hasConceptScore W2910080781C163588942 @default.
- W2910080781 hasConceptScore W2910080781C171250308 @default.
- W2910080781 hasConceptScore W2910080781C178790620 @default.
- W2910080781 hasConceptScore W2910080781C181389837 @default.
- W2910080781 hasConceptScore W2910080781C185592680 @default.
- W2910080781 hasConceptScore W2910080781C192562407 @default.
- W2910080781 hasConceptScore W2910080781C2779820397 @default.
- W2910080781 hasConceptScore W2910080781C2780035454 @default.
- W2910080781 hasConceptScore W2910080781C2780225610 @default.
- W2910080781 hasConceptScore W2910080781C2983812674 @default.
- W2910080781 hasConceptScore W2910080781C71924100 @default.
- W2910080781 hasConceptScore W2910080781C98274493 @default.
- W2910080781 hasLocation W29100807811 @default.
- W2910080781 hasOpenAccess W2910080781 @default.
- W2910080781 hasPrimaryLocation W29100807811 @default.
- W2910080781 hasRelatedWork W1967521101 @default.
- W2910080781 hasRelatedWork W2007067975 @default.
- W2910080781 hasRelatedWork W2029562492 @default.
- W2910080781 hasRelatedWork W2087447402 @default.
- W2910080781 hasRelatedWork W2127227941 @default.
- W2910080781 hasRelatedWork W2168009513 @default.
- W2910080781 hasRelatedWork W2181958695 @default.
- W2910080781 hasRelatedWork W2306738658 @default.
- W2910080781 hasRelatedWork W2347697132 @default.
- W2910080781 hasRelatedWork W2516741164 @default.
- W2910080781 hasRelatedWork W2556791424 @default.
- W2910080781 hasRelatedWork W2565842908 @default.
- W2910080781 hasRelatedWork W2740110507 @default.
- W2910080781 hasRelatedWork W2942048993 @default.
- W2910080781 hasRelatedWork W2951609113 @default.
- W2910080781 hasRelatedWork W2982008618 @default.
- W2910080781 hasRelatedWork W3022090586 @default.
- W2910080781 hasRelatedWork W3119077519 @default.
- W2910080781 hasRelatedWork W74622063 @default.
- W2910080781 hasRelatedWork W2337847613 @default.
- W2910080781 isParatext "false" @default.
- W2910080781 isRetracted "false" @default.
- W2910080781 magId "2910080781" @default.
- W2910080781 workType "article" @default.