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- W2910105868 abstract "Cardiovascular and renal physiology follow strong circadian rhythms. For instance, renal excretion of solutes and water is higher during the active period compared to the inactive period, and blood pressure peaks early in the beginning of the active period of both diurnal and nocturnal animals. The control of these rhythms is largely dependent on the expression of clock genes both in the central nervous system and within peripheral organs themselves. Although it is understood that the central and peripheral clocks interact and communicate, few studies have explored the specific mechanism by which various organ systems within the body are coordinated to control physiological processes. The renal sympathetic nervous innervation has long been known to have profound effects on renal function, and because the sympathetic nervous system follows strong circadian rhythms, it is likely that autonomic control of the kidney plays an integral role in modulating renal circadian function. This review highlights studies that provide insight into this interaction, discusses areas lacking clarity, and suggests the potential for future work to explore the role of renal autonomics in areas such as blood pressure control and chronic kidney disease." @default.
- W2910105868 created "2019-01-25" @default.
- W2910105868 creator A5034901562 @default.
- W2910105868 creator A5058861880 @default.
- W2910105868 creator A5066047278 @default.
- W2910105868 creator A5072196954 @default.
- W2910105868 date "2019-03-01" @default.
- W2910105868 modified "2023-10-18" @default.
- W2910105868 title "Autonomic nerves and circadian control of renal function" @default.
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- W2910105868 doi "https://doi.org/10.1016/j.autneu.2019.01.003" @default.