FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2910130222> ?p ?o ?g. }

• W2910130222 endingPage "155" @default.
• W2910130222 startingPage "147" @default.
• W2910130222 abstract "Despite continuous efforts to prevent cardiovascular diseases (CVDs), heart failure prevails as the number one cause of death in developed countries. To properly treat CVDs, scientists had to take a closer look at the factors that contribute to their pathogenesis and either modernize current pharmaceuticals or develop brand new treatments. Enhancement of current drugs, such as tolvaptan and omecamtiv mecarbil, sheds new light on already-known therapies. Tolvaptan, a vasopressin antagonist, could be adopted in heart failure therapy as it reduces pre- and afterload by decreasing systolic blood pressure and blood volume. Omecamtiv mecarbil, which is a myosin binding peptide, could aid cardiac contractility. The next generation vasodilators, serelaxin and ularitide, are based on naturally occurring peptides and they reduce peripheral vascular resistance and increase the cardiac index. In combination with their anti-inflammatory properties, they could turn out to be extremely potent drugs for heart failure treatment. Cardiotrophin has exceeded many researchers' expectations, as evidence suggests that it could cause sarcomere hypertrophy without excessive proliferation of connective tissue. Rapid progress in gene therapy has caused it to finally be considered as one of the viable options for the treatment of CVDs. This novel therapeutic approach could restore stable heart function either by restoring depleted membrane proteins or by balancing the intracellular calcium concentration. Although it has been set back by problems concerning its long-term effects, it is still highly likely to succeed." @default.
• W2910130222 created "2019-01-25" @default.
• W2910130222 creator A5021724266 @default.
• W2910130222 creator A5038532208 @default.
• W2910130222 creator A5042118147 @default.
• W2910130222 creator A5046363888 @default.
• W2910130222 creator A5056911678 @default.
• W2910130222 creator A5067647094 @default.
• W2910130222 date "2019-01-01" @default.
• W2910130222 modified "2023-10-16" @default.
• W2910130222 title "<p>New therapies for the treatment of heart failure: a summary of recent accomplishments</p>" @default.
• W2910130222 cites W1976277922 @default.
• W2910130222 cites W1992500923 @default.
• W2910130222 cites W1993569315 @default.
• W2910130222 cites W2011139536 @default.
• W2910130222 cites W2024159204 @default.
• W2910130222 cites W2029913374 @default.
• W2910130222 cites W2043260641 @default.
• W2910130222 cites W2064794206 @default.
• W2910130222 cites W2067476313 @default.
• W2910130222 cites W2069270713 @default.
• W2910130222 cites W2076969567 @default.
• W2910130222 cites W2078818919 @default.
• W2910130222 cites W2080482562 @default.
• W2910130222 cites W2085522770 @default.
• W2910130222 cites W2087003082 @default.
• W2910130222 cites W2105784635 @default.
• W2910130222 cites W2111082611 @default.
• W2910130222 cites W2123490348 @default.
• W2910130222 cites W2126777368 @default.
• W2910130222 cites W2128395485 @default.
• W2910130222 cites W2128725121 @default.
• W2910130222 cites W2133228526 @default.
• W2910130222 cites W2133739113 @default.
• W2910130222 cites W2134893281 @default.
• W2910130222 cites W2144431016 @default.
• W2910130222 cites W2160489474 @default.
• W2910130222 cites W2165742125 @default.
• W2910130222 cites W2187004430 @default.
• W2910130222 cites W2221778074 @default.
• W2910130222 cites W2222120722 @default.
• W2910130222 cites W2271175958 @default.
• W2910130222 cites W2279161659 @default.
• W2910130222 cites W2309452508 @default.
• W2910130222 cites W2321407530 @default.
• W2910130222 cites W2345497220 @default.
• W2910130222 cites W2427094903 @default.
• W2910130222 cites W2515683834 @default.
• W2910130222 cites W2530905492 @default.
• W2910130222 cites W2547042452 @default.
• W2910130222 cites W2551617359 @default.
• W2910130222 cites W2576187722 @default.
• W2910130222 cites W2580792129 @default.
• W2910130222 cites W2606853863 @default.
• W2910130222 cites W2609921509 @default.
• W2910130222 cites W2620120354 @default.
• W2910130222 cites W2620919080 @default.
• W2910130222 cites W2726497265 @default.
• W2910130222 cites W2734440134 @default.
• W2910130222 cites W2741413018 @default.
• W2910130222 cites W2742722735 @default.
• W2910130222 cites W2745520514 @default.
• W2910130222 cites W2751448053 @default.
• W2910130222 cites W2767286837 @default.
• W2910130222 doi "https://doi.org/10.2147/tcrm.s179302" @default.
• W2910130222 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6348963" @default.
• W2910130222 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30774351" @default.
• W2910130222 hasPublicationYear "2019" @default.
• W2910130222 type Work @default.
• W2910130222 sameAs 2910130222 @default.
• W2910130222 citedByCount "29" @default.
• W2910130222 countsByYear W29101302222019 @default.
• W2910130222 countsByYear W29101302222020 @default.
• W2910130222 countsByYear W29101302222021 @default.
• W2910130222 countsByYear W29101302222022 @default.
• W2910130222 countsByYear W29101302222023 @default.
• W2910130222 crossrefType "journal-article" @default.
• W2910130222 hasAuthorship W2910130222A5021724266 @default.
• W2910130222 hasAuthorship W2910130222A5038532208 @default.
• W2910130222 hasAuthorship W2910130222A5042118147 @default.
• W2910130222 hasAuthorship W2910130222A5046363888 @default.
• W2910130222 hasAuthorship W2910130222A5056911678 @default.
• W2910130222 hasAuthorship W2910130222A5067647094 @default.
• W2910130222 hasBestOaLocation W29101302221 @default.
• W2910130222 hasConcept C123576724 @default.
• W2910130222 hasConcept C126322002 @default.
• W2910130222 hasConcept C164705383 @default.
• W2910130222 hasConcept C170493617 @default.
• W2910130222 hasConcept C2776885963 @default.
• W2910130222 hasConcept C2778198053 @default.
• W2910130222 hasConcept C2779881253 @default.
• W2910130222 hasConcept C2780615674 @default.
• W2910130222 hasConcept C39133596 @default.
• W2910130222 hasConcept C71924100 @default.
• W2910130222 hasConcept C84393581 @default.
• W2910130222 hasConcept C98274493 @default.
• W2910130222 hasConceptScore W2910130222C123576724 @default.
• W2910130222 hasConceptScore W2910130222C126322002 @default.

• next