Matches in SemOpenAlex for { <https://semopenalex.org/work/W2910142009> ?p ?o ?g. }
- W2910142009 abstract "Context: We conducted a meta-analysis to evaluate the role of the vitamin D receptor (VDR) polymorphism in the risk of hepatocellular carcinoma (HCC) in patients infected with hepatitis B virus (HBV). Objective: To develop new preventions, mechanisms, and therapies for HCC, it is important to investigate the underlying causes of HCC. Recently, there has been increasing attention to the relationship between VDR polymorphism and the risk of HBV-related HCC, but no specific conclusion has been made. Data Sources: PubMed/Medline, EMBASE, Cochrane Library, Chinese National Knowledge Infrastructure, VIP Database for Chinese Technical Periodicals, Wanfang Data, and SINOMED databases were searched until August 2018. Studies reporting VDR polymorphism and HBV-related HCC risks were included and the quality was assessed by Newcastle-Ottawa scale (NOS). Odds ratio (OR) and 95% confidence interval (CI) were calculated to compare the pooled data between HCC risks and different genotypes, such as FF, Ff, F, f, and ff, with each other. Results: Three case-control studies with totally 728 HBV-related HCC cases and 920 HBV controls were included. When comparing HBV-related HCC cases with HBV controls, our data showed that all genotypes of Fok I polymorphism significantly increased the risk of HCC in the overall population (ff vs. FF: OR = 1.816, 95% CI = 1.161 - 2.841, P = 0.0009; Ff vs. FF: OR = 1.315, 95% CI = 1.037 - 1.667, P = 0.024; ff/Ff vs. FF, OR = 1.504, 95% CI = 1.206 - 1.876, P < 0.001; ff vs. FF/Ff: OR = 1.591, 95% CI = 1.270 - 1.992, P < 0.001; ff vs. Ff: OR = 1.435, 95% CI = 1.127 - 1.827, P = 0.003; f vs. F: OR = 1.375, 95% CI = 1.075 - 1.759). Conclusion: The results of our analysis suggest the âfâ allele of Fok I polymorphism might be a risk factor for HCC in HBV-infected patients and it could be a predictive factor to screen HCC in HBV-infected patients. However, more accurate analyses and larger studies are needed." @default.
- W2910142009 created "2019-01-25" @default.
- W2910142009 creator A5001620620 @default.
- W2910142009 creator A5035334515 @default.
- W2910142009 creator A5069010179 @default.
- W2910142009 creator A5070847052 @default.
- W2910142009 creator A5082535694 @default.
- W2910142009 date "2019-01-12" @default.
- W2910142009 modified "2023-10-14" @default.
- W2910142009 title "Vitamin D Receptor Fok I Polymorphism and Risk of Hepatocellular Carcinoma in HBV-Infected Patients" @default.
- W2910142009 cites W1541585098 @default.
- W2910142009 cites W1588037850 @default.
- W2910142009 cites W1810525385 @default.
- W2910142009 cites W1965652126 @default.
- W2910142009 cites W1973391025 @default.
- W2910142009 cites W1979658848 @default.
- W2910142009 cites W1989554921 @default.
- W2910142009 cites W2001693208 @default.
- W2910142009 cites W2015624008 @default.
- W2910142009 cites W2015804728 @default.
- W2910142009 cites W2019967936 @default.
- W2910142009 cites W2021926444 @default.
- W2910142009 cites W2026382086 @default.
- W2910142009 cites W2026637278 @default.
- W2910142009 cites W2053516868 @default.
- W2910142009 cites W2064364170 @default.
- W2910142009 cites W2071476028 @default.
- W2910142009 cites W2076353670 @default.
- W2910142009 cites W2093359666 @default.
- W2910142009 cites W2100982243 @default.
- W2910142009 cites W2103637700 @default.
- W2910142009 cites W2119287821 @default.
- W2910142009 cites W2120241921 @default.
- W2910142009 cites W2120970673 @default.
- W2910142009 cites W2126617070 @default.
- W2910142009 cites W2137052325 @default.
- W2910142009 cites W2138996074 @default.
- W2910142009 cites W2143565640 @default.
- W2910142009 cites W2145595073 @default.
- W2910142009 cites W2146743869 @default.
- W2910142009 cites W2154239359 @default.
- W2910142009 cites W2158914520 @default.
- W2910142009 cites W2161053030 @default.
- W2910142009 cites W2170633125 @default.
- W2910142009 cites W2583804433 @default.
- W2910142009 cites W2625419650 @default.
- W2910142009 cites W2771095184 @default.
- W2910142009 doi "https://doi.org/10.5812/hepatmon.85075" @default.
- W2910142009 hasPublicationYear "2019" @default.
- W2910142009 type Work @default.
- W2910142009 sameAs 2910142009 @default.
- W2910142009 citedByCount "0" @default.
- W2910142009 crossrefType "journal-article" @default.
- W2910142009 hasAuthorship W2910142009A5001620620 @default.
- W2910142009 hasAuthorship W2910142009A5035334515 @default.
- W2910142009 hasAuthorship W2910142009A5069010179 @default.
- W2910142009 hasAuthorship W2910142009A5070847052 @default.
- W2910142009 hasAuthorship W2910142009A5082535694 @default.
- W2910142009 hasBestOaLocation W29101420091 @default.
- W2910142009 hasConcept C104317684 @default.
- W2910142009 hasConcept C124490489 @default.
- W2910142009 hasConcept C126322002 @default.
- W2910142009 hasConcept C135763542 @default.
- W2910142009 hasConcept C143998085 @default.
- W2910142009 hasConcept C156957248 @default.
- W2910142009 hasConcept C179639408 @default.
- W2910142009 hasConcept C203014093 @default.
- W2910142009 hasConcept C2522874641 @default.
- W2910142009 hasConcept C2776478404 @default.
- W2910142009 hasConcept C2777382497 @default.
- W2910142009 hasConcept C2778019345 @default.
- W2910142009 hasConcept C2780593183 @default.
- W2910142009 hasConcept C44249647 @default.
- W2910142009 hasConcept C54355233 @default.
- W2910142009 hasConcept C71924100 @default.
- W2910142009 hasConcept C86803240 @default.
- W2910142009 hasConcept C90924648 @default.
- W2910142009 hasConcept C95190672 @default.
- W2910142009 hasConceptScore W2910142009C104317684 @default.
- W2910142009 hasConceptScore W2910142009C124490489 @default.
- W2910142009 hasConceptScore W2910142009C126322002 @default.
- W2910142009 hasConceptScore W2910142009C135763542 @default.
- W2910142009 hasConceptScore W2910142009C143998085 @default.
- W2910142009 hasConceptScore W2910142009C156957248 @default.
- W2910142009 hasConceptScore W2910142009C179639408 @default.
- W2910142009 hasConceptScore W2910142009C203014093 @default.
- W2910142009 hasConceptScore W2910142009C2522874641 @default.
- W2910142009 hasConceptScore W2910142009C2776478404 @default.
- W2910142009 hasConceptScore W2910142009C2777382497 @default.
- W2910142009 hasConceptScore W2910142009C2778019345 @default.
- W2910142009 hasConceptScore W2910142009C2780593183 @default.
- W2910142009 hasConceptScore W2910142009C44249647 @default.
- W2910142009 hasConceptScore W2910142009C54355233 @default.
- W2910142009 hasConceptScore W2910142009C71924100 @default.
- W2910142009 hasConceptScore W2910142009C86803240 @default.
- W2910142009 hasConceptScore W2910142009C90924648 @default.
- W2910142009 hasConceptScore W2910142009C95190672 @default.
- W2910142009 hasIssue "In Press" @default.
- W2910142009 hasLocation W29101420091 @default.
- W2910142009 hasOpenAccess W2910142009 @default.