Matches in SemOpenAlex for { <https://semopenalex.org/work/W2910201624> ?p ?o ?g. }
- W2910201624 endingPage "1085" @default.
- W2910201624 startingPage "1071" @default.
- W2910201624 abstract "Mature B cell lymphomas account for approximately 60% of all cases of non-Hodgkin lymphoma (NHL) in children and adolescents and includes Burkitt lymphoma (BL), diffuse large B cell lymphoma (DLBCL) and other less common histologies. The outcome for patients treated with modern regimens in resource-intensive settings is excellent. Improvements in care have been accomplished through enhanced supportive therapy, including tumour lysis management and incremental refinement of chemotherapy backbones via cooperative group clinical trials in which patients receive risk group-specific intensive chemotherapy. More recent trials have established the safety and efficacy of immunotherapy. Ongoing work is required to address the substantial burden of acute therapy-related toxicity, as well as the identification of effective therapies for those patients with relapsed and refractory disease, for whom outcomes remain very poor. In this review we will summarize the results from recent therapeutic clinical trials, describe the evidence to support the inclusion of rituximab and review the rationale for the investigation of several new categories of novel agents for mature B cell lymphomas in children and adolescents." @default.
- W2910201624 created "2019-01-25" @default.
- W2910201624 creator A5005194121 @default.
- W2910201624 creator A5018285747 @default.
- W2910201624 creator A5033277609 @default.
- W2910201624 date "2019-01-06" @default.
- W2910201624 modified "2023-10-17" @default.
- W2910201624 title "Mature B‐<scp>NHL</scp> in children, adolescents and young adults: current therapeutic approach and emerging treatment strategies" @default.
- W2910201624 cites W1020989877 @default.
- W2910201624 cites W1909235015 @default.
- W2910201624 cites W1938144043 @default.
- W2910201624 cites W1974184061 @default.
- W2910201624 cites W1978905721 @default.
- W2910201624 cites W1988779324 @default.
- W2910201624 cites W1995314727 @default.
- W2910201624 cites W1997647834 @default.
- W2910201624 cites W1998851035 @default.
- W2910201624 cites W1999105034 @default.
- W2910201624 cites W1999893418 @default.
- W2910201624 cites W2000871066 @default.
- W2910201624 cites W2005559053 @default.
- W2910201624 cites W2006709900 @default.
- W2910201624 cites W2008143837 @default.
- W2910201624 cites W2010711123 @default.
- W2910201624 cites W2015098191 @default.
- W2910201624 cites W2019874087 @default.
- W2910201624 cites W2031180703 @default.
- W2910201624 cites W2031333117 @default.
- W2910201624 cites W2031885687 @default.
- W2910201624 cites W2045940197 @default.
- W2910201624 cites W2047522348 @default.
- W2910201624 cites W2050529097 @default.
- W2910201624 cites W2056545314 @default.
- W2910201624 cites W2058015212 @default.
- W2910201624 cites W2060466778 @default.
- W2910201624 cites W2067257663 @default.
- W2910201624 cites W2070872496 @default.
- W2910201624 cites W2073127483 @default.
- W2910201624 cites W2077362224 @default.
- W2910201624 cites W2077522084 @default.
- W2910201624 cites W2078069330 @default.
- W2910201624 cites W2084201114 @default.
- W2910201624 cites W2093744470 @default.
- W2910201624 cites W2100842411 @default.
- W2910201624 cites W2105396178 @default.
- W2910201624 cites W2111500154 @default.
- W2910201624 cites W2116294628 @default.
- W2910201624 cites W2118028844 @default.
- W2910201624 cites W2126779595 @default.
- W2910201624 cites W2126855868 @default.
- W2910201624 cites W2133131759 @default.
- W2910201624 cites W2133155058 @default.
- W2910201624 cites W2134766521 @default.
- W2910201624 cites W2136725907 @default.
- W2910201624 cites W2143901303 @default.
- W2910201624 cites W2144594787 @default.
- W2910201624 cites W2147086069 @default.
- W2910201624 cites W2147246240 @default.
- W2910201624 cites W2158007545 @default.
- W2910201624 cites W2158957674 @default.
- W2910201624 cites W2159263318 @default.
- W2910201624 cites W2160305510 @default.
- W2910201624 cites W2161054245 @default.
- W2910201624 cites W2162244898 @default.
- W2910201624 cites W2164433065 @default.
- W2910201624 cites W2236959863 @default.
- W2910201624 cites W2279127916 @default.
- W2910201624 cites W2310716991 @default.
- W2910201624 cites W2334417343 @default.
- W2910201624 cites W2417043811 @default.
- W2910201624 cites W2419639370 @default.
- W2910201624 cites W2504729294 @default.
- W2910201624 cites W2513177163 @default.
- W2910201624 cites W2529226476 @default.
- W2910201624 cites W2551804989 @default.
- W2910201624 cites W2558797931 @default.
- W2910201624 cites W2566018578 @default.
- W2910201624 cites W2582696216 @default.
- W2910201624 cites W2588109600 @default.
- W2910201624 cites W2591709377 @default.
- W2910201624 cites W2593648047 @default.
- W2910201624 cites W2594602128 @default.
- W2910201624 cites W2595477151 @default.
- W2910201624 cites W2595802803 @default.
- W2910201624 cites W2605767476 @default.
- W2910201624 cites W2612422239 @default.
- W2910201624 cites W2622207627 @default.
- W2910201624 cites W2642730068 @default.
- W2910201624 cites W2725925241 @default.
- W2910201624 cites W2729141564 @default.
- W2910201624 cites W2733090892 @default.
- W2910201624 cites W2742627598 @default.
- W2910201624 cites W2751075585 @default.
- W2910201624 cites W2763994374 @default.
- W2910201624 cites W2765486607 @default.
- W2910201624 cites W2768823259 @default.
- W2910201624 cites W2771658548 @default.
- W2910201624 cites W2773804840 @default.