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- W2910257966 abstract "Bone histomorphometry allows accurate evaluation not only of bone mass and turnover but also of bone microarchitecture Microscopic examination of bone biopsied from the iliac crest after in vivo tetracycline labeling permits separate assessments of cortical and cancellous bone, a clear advantage over noninvasive methods of bone mass measurement, which can provide only indirect information in this regard. This technique has clinical applications in selected disorders— such as primary hyperparathyroidism, where it allows the detection of abnormalities of bone turnover, even in asymptomatic subjects showing no radiologic evidence of bone disease. In spite of limitations inherent in the small size of the biopsy sample and regional variations among skeletal sites, the iliac crest site is generally considered to represent both the structure and the metabolic processes that affect the entire skeleton. A histomorphometric study confirmed the accelerated rate of bone remodeling in primary hyperparathyroidism. In a group of subjects with mild primary hyperparathyroidism, there was a two to three fold increase in the values of static and dynamic turnover indices." @default.
- W2910257966 created "2019-01-25" @default.
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- W2910257966 date "2001-01-01" @default.
- W2910257966 modified "2023-10-10" @default.
- W2910257966 title "Histomorphometric Analysis of Bone in Primary Hyperparathyroidism" @default.
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