FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2910277584> ?p ?o ?g. }

• W2910277584 endingPage "e0209124" @default.
• W2910277584 startingPage "e0209124" @default.
• W2910277584 abstract "Today's beer market is challenged by a decreasing consumption of traditional beer styles and an increasing consumption of specialty beers. In particular, lager-type beers (pilsner), characterized by their refreshing and unique aroma and taste, yet very uniform, struggle with their sales. The development of novel variants of the common lager yeast, the interspecific hybrid Saccharomyces pastorianus, has been proposed as a possible solution to address the need of product diversification in lager beers. Previous efforts to generate new lager yeasts through hybridization of the ancestral parental species (S. cerevisiae and S. eubayanus) yielded strains with an aromatic profile distinct from the natural biodiversity. Unfortunately, next to the desired properties, these novel yeasts also inherited unwanted characteristics. Most notably is their phenolic off-flavor (POF) production, which hampers their direct application in the industrial production processes. Here, we describe a CRISPR-based gene editing strategy that allows the systematic and meticulous introduction of a natural occurring mutation in the FDC1 gene of genetically complex industrial S. cerevisiae strains, S. eubayanus yeasts and interspecific hybrids. The resulting cisgenic POF- variants show great potential for industrial application and diversifying the current lager beer portfolio." @default.
• W2910277584 created "2019-01-25" @default.
• W2910277584 creator A5002834174 @default.
• W2910277584 creator A5017796555 @default.
• W2910277584 creator A5019531017 @default.
• W2910277584 creator A5024721481 @default.
• W2910277584 creator A5026180830 @default.
• W2910277584 creator A5040048397 @default.
• W2910277584 creator A5076669148 @default.
• W2910277584 creator A5057440039 @default.
• W2910277584 date "2019-01-09" @default.
• W2910277584 modified "2023-10-09" @default.
• W2910277584 title "Reducing phenolic off-flavors through CRISPR-based gene editing of the FDC1 gene in Saccharomyces cerevisiae x Saccharomyces eubayanus hybrid lager beer yeasts" @default.
• W2910277584 cites W1557238147 @default.
• W2910277584 cites W1975837950 @default.
• W2910277584 cites W1979415385 @default.
• W2910277584 cites W1979782327 @default.
• W2910277584 cites W1986188838 @default.
• W2910277584 cites W2001975333 @default.
• W2910277584 cites W2002227940 @default.
• W2910277584 cites W2016033442 @default.
• W2910277584 cites W2019669275 @default.
• W2910277584 cites W2030631404 @default.
• W2910277584 cites W2039705224 @default.
• W2910277584 cites W2045055145 @default.
• W2910277584 cites W2050829599 @default.
• W2910277584 cites W2052558282 @default.
• W2910277584 cites W2060983149 @default.
• W2910277584 cites W2062819607 @default.
• W2910277584 cites W2069981581 @default.
• W2910277584 cites W2075396966 @default.
• W2910277584 cites W2077724722 @default.
• W2910277584 cites W2077901898 @default.
• W2910277584 cites W2085258287 @default.
• W2910277584 cites W2089344799 @default.
• W2910277584 cites W2095725097 @default.
• W2910277584 cites W2096309756 @default.
• W2910277584 cites W2106116311 @default.
• W2910277584 cites W2107835138 @default.
• W2910277584 cites W2113928662 @default.
• W2910277584 cites W2117247186 @default.
• W2910277584 cites W2120772351 @default.
• W2910277584 cites W2137253682 @default.
• W2910277584 cites W2142907337 @default.
• W2910277584 cites W2143580579 @default.
• W2910277584 cites W2146503498 @default.
• W2910277584 cites W2151699165 @default.
• W2910277584 cites W2152021404 @default.
• W2910277584 cites W2160246565 @default.
• W2910277584 cites W2167402896 @default.
• W2910277584 cites W2169333620 @default.
• W2910277584 cites W2174397560 @default.
• W2910277584 cites W2232184032 @default.
• W2910277584 cites W2337748739 @default.
• W2910277584 cites W2508506323 @default.
• W2910277584 cites W2561823070 @default.
• W2910277584 cites W2605830991 @default.
• W2910277584 cites W2608059898 @default.
• W2910277584 cites W2616246638 @default.
• W2910277584 cites W2620919450 @default.
• W2910277584 cites W2623597117 @default.
• W2910277584 cites W2740965583 @default.
• W2910277584 cites W2768890109 @default.
• W2910277584 cites W2772277102 @default.
• W2910277584 cites W2774977952 @default.
• W2910277584 cites W2791721391 @default.
• W2910277584 cites W2802265359 @default.
• W2910277584 cites W2802860499 @default.
• W2910277584 cites W2884011497 @default.
• W2910277584 cites W2891194988 @default.
• W2910277584 cites W72965807 @default.
• W2910277584 doi "https://doi.org/10.1371/journal.pone.0209124" @default.
• W2910277584 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6812760" @default.
• W2910277584 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31648239" @default.
• W2910277584 hasPublicationYear "2019" @default.
• W2910277584 type Work @default.
• W2910277584 sameAs 2910277584 @default.
• W2910277584 citedByCount "20" @default.
• W2910277584 countsByYear W29102775842019 @default.
• W2910277584 countsByYear W29102775842020 @default.
• W2910277584 countsByYear W29102775842021 @default.
• W2910277584 countsByYear W29102775842022 @default.
• W2910277584 countsByYear W29102775842023 @default.
• W2910277584 crossrefType "journal-article" @default.
• W2910277584 hasAuthorship W2910277584A5002834174 @default.
• W2910277584 hasAuthorship W2910277584A5017796555 @default.
• W2910277584 hasAuthorship W2910277584A5019531017 @default.
• W2910277584 hasAuthorship W2910277584A5024721481 @default.
• W2910277584 hasAuthorship W2910277584A5026180830 @default.
• W2910277584 hasAuthorship W2910277584A5040048397 @default.
• W2910277584 hasAuthorship W2910277584A5057440039 @default.
• W2910277584 hasAuthorship W2910277584A5076669148 @default.
• W2910277584 hasBestOaLocation W29102775841 @default.
• W2910277584 hasConcept C104317684 @default.
• W2910277584 hasConcept C150903083 @default.
• W2910277584 hasConcept C2777576037 @default.
• W2910277584 hasConcept C2778447961 @default.
• W2910277584 hasConcept C54355233 @default.

• next