Matches in SemOpenAlex for { <https://semopenalex.org/work/W2910361792> ?p ?o ?g. }
- W2910361792 abstract "Influenza A viruses (IAV) constitute a major public health issue, causing illness and death in high-risk populations during seasonal epidemics or pandemics. IAV are known to modulate cellular pathways to promote their replication and avoid immune restriction via the targeting of several cellular proteins. One of these proteins, p53, is a master regulator involved in a large panel of biological processes, including cell cycle arrest, apoptosis, or senescence. This “cellular gatekeeper” is also involved in the control of viral infections, and viruses have developed a wide diversity of mechanisms to modulate/hijack p53 functions to achieve an optimal replication in their hosts. Our group and others have previously shown that p53 activity is finely modulated by different multilevel mechanisms during IAV infection. Here, we characterized IAV nonstructural protein NS1 and the cellular factor CPSF4 as major partners involved in the IAV-induced modulation of the TP53 alternative splicing that was associated with a strong modulation of p53 activity and notably the p53-mediated antiviral response." @default.
- W2910361792 created "2019-01-25" @default.
- W2910361792 creator A5003087042 @default.
- W2910361792 creator A5005935743 @default.
- W2910361792 creator A5010328570 @default.
- W2910361792 creator A5032814977 @default.
- W2910361792 creator A5033309280 @default.
- W2910361792 creator A5042500741 @default.
- W2910361792 creator A5043361043 @default.
- W2910361792 creator A5074097531 @default.
- W2910361792 creator A5074553554 @default.
- W2910361792 creator A5080910597 @default.
- W2910361792 date "2019-04-01" @default.
- W2910361792 modified "2023-10-14" @default.
- W2910361792 title "The Nonstructural NS1 Protein of Influenza Viruses Modulates <i>TP53</i> Splicing through Host Factor CPSF4" @default.
- W2910361792 cites W1514597103 @default.
- W2910361792 cites W1566453842 @default.
- W2910361792 cites W1581523186 @default.
- W2910361792 cites W1611904685 @default.
- W2910361792 cites W1695062097 @default.
- W2910361792 cites W1828028114 @default.
- W2910361792 cites W1877576531 @default.
- W2910361792 cites W1890766043 @default.
- W2910361792 cites W1964709641 @default.
- W2910361792 cites W1965886912 @default.
- W2910361792 cites W1984229543 @default.
- W2910361792 cites W1986144600 @default.
- W2910361792 cites W1991297120 @default.
- W2910361792 cites W1992479402 @default.
- W2910361792 cites W1995550922 @default.
- W2910361792 cites W1998997956 @default.
- W2910361792 cites W1999352184 @default.
- W2910361792 cites W2003627913 @default.
- W2910361792 cites W2003805923 @default.
- W2910361792 cites W2004586645 @default.
- W2910361792 cites W2008332711 @default.
- W2910361792 cites W2009627733 @default.
- W2910361792 cites W2015519364 @default.
- W2910361792 cites W2020743575 @default.
- W2910361792 cites W2021800980 @default.
- W2910361792 cites W2027706180 @default.
- W2910361792 cites W2037972726 @default.
- W2910361792 cites W2045086385 @default.
- W2910361792 cites W2051973387 @default.
- W2910361792 cites W2060173726 @default.
- W2910361792 cites W2070924692 @default.
- W2910361792 cites W2074410038 @default.
- W2910361792 cites W2078724846 @default.
- W2910361792 cites W2079674245 @default.
- W2910361792 cites W2089911961 @default.
- W2910361792 cites W2091151415 @default.
- W2910361792 cites W2110214166 @default.
- W2910361792 cites W2114172480 @default.
- W2910361792 cites W2115612309 @default.
- W2910361792 cites W2119885778 @default.
- W2910361792 cites W2127096557 @default.
- W2910361792 cites W2135187368 @default.
- W2910361792 cites W2138878175 @default.
- W2910361792 cites W2142180745 @default.
- W2910361792 cites W2155570392 @default.
- W2910361792 cites W2158746638 @default.
- W2910361792 cites W2161105855 @default.
- W2910361792 cites W2162563329 @default.
- W2910361792 cites W2163853272 @default.
- W2910361792 cites W2165667087 @default.
- W2910361792 cites W2264082883 @default.
- W2910361792 cites W2279174688 @default.
- W2910361792 cites W2408181412 @default.
- W2910361792 cites W2527179423 @default.
- W2910361792 cites W2561408151 @default.
- W2910361792 cites W2606845734 @default.
- W2910361792 cites W2615340866 @default.
- W2910361792 cites W2617564580 @default.
- W2910361792 cites W27023215 @default.
- W2910361792 cites W317634691 @default.
- W2910361792 cites W38265209 @default.
- W2910361792 cites W4211090574 @default.
- W2910361792 doi "https://doi.org/10.1128/jvi.02168-18" @default.
- W2910361792 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6430556" @default.
- W2910361792 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30651364" @default.
- W2910361792 hasPublicationYear "2019" @default.
- W2910361792 type Work @default.
- W2910361792 sameAs 2910361792 @default.
- W2910361792 citedByCount "20" @default.
- W2910361792 countsByYear W29103617922019 @default.
- W2910361792 countsByYear W29103617922020 @default.
- W2910361792 countsByYear W29103617922021 @default.
- W2910361792 countsByYear W29103617922022 @default.
- W2910361792 countsByYear W29103617922023 @default.
- W2910361792 crossrefType "journal-article" @default.
- W2910361792 hasAuthorship W2910361792A5003087042 @default.
- W2910361792 hasAuthorship W2910361792A5005935743 @default.
- W2910361792 hasAuthorship W2910361792A5010328570 @default.
- W2910361792 hasAuthorship W2910361792A5032814977 @default.
- W2910361792 hasAuthorship W2910361792A5033309280 @default.
- W2910361792 hasAuthorship W2910361792A5042500741 @default.
- W2910361792 hasAuthorship W2910361792A5043361043 @default.
- W2910361792 hasAuthorship W2910361792A5074097531 @default.
- W2910361792 hasAuthorship W2910361792A5074553554 @default.
- W2910361792 hasAuthorship W2910361792A5080910597 @default.