Matches in SemOpenAlex for { <https://semopenalex.org/work/W2910463736> ?p ?o ?g. }
- W2910463736 endingPage "807" @default.
- W2910463736 startingPage "798" @default.
- W2910463736 abstract "Rotavirus disease in Mongolia is estimated to cause more than 50 deaths yearly and many more cases and hospitalizations. Mongolia must self-finance new vaccines and does not automatically access Gavi prices for vaccines. Given the country’s limited resources for health, it is critical to assess potential new vaccine programs. This evaluation estimates the impact, cost-effectiveness, and budget implications associated with a nationwide rotavirus vaccine introduction targeting infants as part of the national immunization program in Mongolia, in order to inform decision-making around introduction. The analysis examines the use of the two-dose vaccine ROTARIX®, and three-dose vaccines ROTAVAC® and RotaTeq® compared to no vaccination from the government and the societal perspective. We use a modelling approach informed by local data and published literature to analyze the impact and cost-effectiveness of rotavirus vaccination over a ten-year time period starting in 2019, using a 3% discount rate. Our main outcome measure is the incremental cost-effectiveness ratio (ICER) expressed as US dollar per DALY averted. We assessed uncertainty around a series of parameters through univariate sensitivity analysis. Rotavirus vaccination in Mongolia could avert more than 95,000 rotavirus cases and 271 deaths, over 10 years. Averted visits and hospitalizations represent US$2.4 million in health care costs saved by the government. The vaccination program cost ranges from $6 to $11 million depending on vaccine choice. From the governmental perspective, ICER ranged from $412 to $1050 and from $77 to $715 when considering the societal perspective. Sensitivity analysis highlights vaccine price as the main driver of uncertainty. Introduction of rotavirus vaccination is likely to be highly cost-effective in Mongolia, with ICERs estimated at only a fraction of Mongolia’s per capita GDP. From an economic standpoint, ROTAVAC® is the least costly and most cost-effective product choice." @default.
- W2910463736 created "2019-01-25" @default.
- W2910463736 creator A5013246785 @default.
- W2910463736 creator A5014704864 @default.
- W2910463736 creator A5033151792 @default.
- W2910463736 creator A5046887363 @default.
- W2910463736 creator A5061848201 @default.
- W2910463736 creator A5062579927 @default.
- W2910463736 creator A5067233239 @default.
- W2910463736 creator A5073644479 @default.
- W2910463736 creator A5081913349 @default.
- W2910463736 creator A5089513385 @default.
- W2910463736 date "2019-02-01" @default.
- W2910463736 modified "2023-10-16" @default.
- W2910463736 title "Projected impact, cost-effectiveness, and budget implications of rotavirus vaccination in Mongolia" @default.
- W2910463736 cites W1983888495 @default.
- W2910463736 cites W2031363511 @default.
- W2910463736 cites W2098900210 @default.
- W2910463736 cites W2101380815 @default.
- W2910463736 cites W2135985984 @default.
- W2910463736 cites W2149698613 @default.
- W2910463736 cites W2158543557 @default.
- W2910463736 cites W2328134362 @default.
- W2910463736 cites W2329002331 @default.
- W2910463736 cites W2557867537 @default.
- W2910463736 cites W2577758058 @default.
- W2910463736 cites W2614075575 @default.
- W2910463736 cites W2755856084 @default.
- W2910463736 cites W2793747534 @default.
- W2910463736 cites W2898307104 @default.
- W2910463736 cites W2990708878 @default.
- W2910463736 cites W38628352 @default.
- W2910463736 cites W4292435229 @default.
- W2910463736 doi "https://doi.org/10.1016/j.vaccine.2018.12.056" @default.
- W2910463736 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6357530" @default.
- W2910463736 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30639458" @default.
- W2910463736 hasPublicationYear "2019" @default.
- W2910463736 type Work @default.
- W2910463736 sameAs 2910463736 @default.
- W2910463736 citedByCount "11" @default.
- W2910463736 countsByYear W29104637362019 @default.
- W2910463736 countsByYear W29104637362020 @default.
- W2910463736 countsByYear W29104637362021 @default.
- W2910463736 countsByYear W29104637362022 @default.
- W2910463736 countsByYear W29104637362023 @default.
- W2910463736 crossrefType "journal-article" @default.
- W2910463736 hasAuthorship W2910463736A5013246785 @default.
- W2910463736 hasAuthorship W2910463736A5014704864 @default.
- W2910463736 hasAuthorship W2910463736A5033151792 @default.
- W2910463736 hasAuthorship W2910463736A5046887363 @default.
- W2910463736 hasAuthorship W2910463736A5061848201 @default.
- W2910463736 hasAuthorship W2910463736A5062579927 @default.
- W2910463736 hasAuthorship W2910463736A5067233239 @default.
- W2910463736 hasAuthorship W2910463736A5073644479 @default.
- W2910463736 hasAuthorship W2910463736A5081913349 @default.
- W2910463736 hasAuthorship W2910463736A5089513385 @default.
- W2910463736 hasBestOaLocation W29104637361 @default.
- W2910463736 hasConcept C112930515 @default.
- W2910463736 hasConcept C127454912 @default.
- W2910463736 hasConcept C138885662 @default.
- W2910463736 hasConcept C147483822 @default.
- W2910463736 hasConcept C17744445 @default.
- W2910463736 hasConcept C187212893 @default.
- W2910463736 hasConcept C199539241 @default.
- W2910463736 hasConcept C203014093 @default.
- W2910463736 hasConcept C22070199 @default.
- W2910463736 hasConcept C2522874641 @default.
- W2910463736 hasConcept C2777227250 @default.
- W2910463736 hasConcept C2778137410 @default.
- W2910463736 hasConcept C2780801004 @default.
- W2910463736 hasConcept C2781367151 @default.
- W2910463736 hasConcept C3019080777 @default.
- W2910463736 hasConcept C41895202 @default.
- W2910463736 hasConcept C515549039 @default.
- W2910463736 hasConcept C71924100 @default.
- W2910463736 hasConcept C99454951 @default.
- W2910463736 hasConceptScore W2910463736C112930515 @default.
- W2910463736 hasConceptScore W2910463736C127454912 @default.
- W2910463736 hasConceptScore W2910463736C138885662 @default.
- W2910463736 hasConceptScore W2910463736C147483822 @default.
- W2910463736 hasConceptScore W2910463736C17744445 @default.
- W2910463736 hasConceptScore W2910463736C187212893 @default.
- W2910463736 hasConceptScore W2910463736C199539241 @default.
- W2910463736 hasConceptScore W2910463736C203014093 @default.
- W2910463736 hasConceptScore W2910463736C22070199 @default.
- W2910463736 hasConceptScore W2910463736C2522874641 @default.
- W2910463736 hasConceptScore W2910463736C2777227250 @default.
- W2910463736 hasConceptScore W2910463736C2778137410 @default.
- W2910463736 hasConceptScore W2910463736C2780801004 @default.
- W2910463736 hasConceptScore W2910463736C2781367151 @default.
- W2910463736 hasConceptScore W2910463736C3019080777 @default.
- W2910463736 hasConceptScore W2910463736C41895202 @default.
- W2910463736 hasConceptScore W2910463736C515549039 @default.
- W2910463736 hasConceptScore W2910463736C71924100 @default.
- W2910463736 hasConceptScore W2910463736C99454951 @default.
- W2910463736 hasFunder F4320306137 @default.
- W2910463736 hasIssue "6" @default.
- W2910463736 hasLocation W29104637361 @default.