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• W2910706034 abstract "Purpose To evaluate the performance of preoperative ultrasound in the diagnosis of cervical lymph nodes metastases (CLNM) of papillary thyroid cancer (PTC) and its value in assisting cervical lymph node dissection (CLND). Methods PubMed, EMBASE and Cochrane Library databases were searched to identify relevant studies up to Sep. 2017. Overall sensitivity, specificity, and diagnostic odds ratio (DOR) were used to assess the diagnostic efficacy of ultrasound in detecting central and lateral CLNM of PTC. Results Nineteen studies comprising 4014 patients were included in the meta-analysis. The pooled sensitivity, specificity, DOR and area under curve (AUC) of ultrasound in detecting central CLNM were 0.33 (95% confidence interval (95% CI): 0.31–0.35), 0.93 (95% CI: 0.92–0.94), 5.63 (95% CI: 3.50–9.04), and 0.69, respectively; and lateral CLNM were 0.70 (95% CI: 0.68–0.72), 0.84 (95% CI: 0.82–0.85), 18.7 (95% CI: 10.3–33.9) and 0.88, respectively. We found that the rate of central CLNM of PTC was 48.0%, and 36.2% of the dissected lymph nodes were metastatic, meanwhile, the rate of lateral CLNM of PTC was 59.2%, and 46.6% of the dissected lymph nodes were metastatic in the meta-analysis. Conclusions Preoperative ultrasound demonstrates poor sensitivity in the diagnosis of central CLNM, and good diagnostic efficacy for lateral CLNM of PTC. Prophylactic central CLND is recommended to PTC patients due to the high incidence of central CLNM and low diagnostic efficacy of ultrasound." @default.
• W2910706034 created "2019-01-25" @default.
• W2910706034 creator A5066811658 @default.
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• W2910706034 date "2019-03-01" @default.
• W2910706034 modified "2023-09-30" @default.
• W2910706034 title "Meta-analysis of ultrasound for cervical lymph nodes in papillary thyroid cancer: Diagnosis of central and lateral compartment nodal metastases" @default.
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• W2910706034 doi "https://doi.org/10.1016/j.ejrad.2019.01.006" @default.
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