FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2910733642> ?p ?o ?g. }

• W2910733642 abstract "Background: Lung cancer is the leading cause of death, related to cancer in both men and women. MicroRNAs (miRNAs) play key roles in regulating the genes that are responsible for apoptosis, and regulation of gene expression. MicroRNA expression is deregulated in cancer. Many efforts have been made to detect cancer biomarkers. Extracellular miRNAs, which are directly released from tumors, can be detected in circulating blood. Objectives: The aim of this study was to examine the expression of miRNA-205 and -21 in lung cancer patients relative to healthy controls. Methods: This cross sectional study was performed in 50 healthy blood sample controls and 50 non-small cell lung cancer (NSCLC) blood samples. The expression of two miRNAs (miR-21 and miR-205) in peripheral blood mononuclear cells (PBMCs) was evaluated, using real-time polymerase chain reaction (real-time PCR) techniques. Statistical tests were carried out via the Mann-Whitney test. Results: The miR-205 levels of expression in the patients with lung cancer significantly increased in comparison to healthy controls (6.8 ± 0.42 and 1.2 ± 0.19, respectively), (P = 0.014). The expression of miR-21 in lung cancer (5.2 ± 0.52) significantly increased compared to the control group (1.6 ± 0.14) (P < 0.001). Conclusions: Based on our findings, lung cancer can enhance the ectopic expression of several miRNAs, which, in turn, play key roles in impaired apoptosis and further cancerous progression." @default.
• W2910733642 created "2019-01-25" @default.
• W2910733642 creator A5004861157 @default.
• W2910733642 creator A5005460072 @default.
• W2910733642 creator A5010827654 @default.
• W2910733642 creator A5012992731 @default.
• W2910733642 creator A5014303439 @default.
• W2910733642 creator A5020210629 @default.
• W2910733642 creator A5021316199 @default.
• W2910733642 creator A5033341099 @default.
• W2910733642 creator A5041806630 @default.
• W2910733642 creator A5060651076 @default.
• W2910733642 creator A5073945430 @default.
• W2910733642 creator A5088634553 @default.
• W2910733642 date "2019-01-19" @default.
• W2910733642 modified "2023-10-14" @default.
• W2910733642 title "Ectopic Expression of miRNA-21 and miRNA-205 in Non-Small Cell Lung Cancer" @default.
• W2910733642 cites W1845230790 @default.
• W2910733642 cites W1973850915 @default.
• W2910733642 cites W1982883752 @default.
• W2910733642 cites W1990079648 @default.
• W2910733642 cites W2006797972 @default.
• W2910733642 cites W2024098388 @default.
• W2910733642 cites W2024206172 @default.
• W2910733642 cites W2037011799 @default.
• W2910733642 cites W2040196718 @default.
• W2910733642 cites W2051742304 @default.
• W2910733642 cites W2063770678 @default.
• W2910733642 cites W2069489023 @default.
• W2910733642 cites W2072378401 @default.
• W2910733642 cites W2084185995 @default.
• W2910733642 cites W2092913756 @default.
• W2910733642 cites W2100104641 @default.
• W2910733642 cites W2103099549 @default.
• W2910733642 cites W2103950317 @default.
• W2910733642 cites W2104610341 @default.
• W2910733642 cites W2112187582 @default.
• W2910733642 cites W2115093090 @default.
• W2910733642 cites W2115210097 @default.
• W2910733642 cites W2118783465 @default.
• W2910733642 cites W57303695 @default.
• W2910733642 doi "https://doi.org/10.5812/ijcm.85456" @default.
• W2910733642 hasPublicationYear "2019" @default.
• W2910733642 type Work @default.
• W2910733642 sameAs 2910733642 @default.
• W2910733642 citedByCount "3" @default.
• W2910733642 countsByYear W29107336422022 @default.
• W2910733642 crossrefType "journal-article" @default.
• W2910733642 hasAuthorship W2910733642A5004861157 @default.
• W2910733642 hasAuthorship W2910733642A5005460072 @default.
• W2910733642 hasAuthorship W2910733642A5010827654 @default.
• W2910733642 hasAuthorship W2910733642A5012992731 @default.
• W2910733642 hasAuthorship W2910733642A5014303439 @default.
• W2910733642 hasAuthorship W2910733642A5020210629 @default.
• W2910733642 hasAuthorship W2910733642A5021316199 @default.
• W2910733642 hasAuthorship W2910733642A5033341099 @default.
• W2910733642 hasAuthorship W2910733642A5041806630 @default.
• W2910733642 hasAuthorship W2910733642A5060651076 @default.
• W2910733642 hasAuthorship W2910733642A5073945430 @default.
• W2910733642 hasAuthorship W2910733642A5088634553 @default.
• W2910733642 hasBestOaLocation W29107336421 @default.
• W2910733642 hasConcept C104317684 @default.
• W2910733642 hasConcept C121608353 @default.
• W2910733642 hasConcept C126322002 @default.
• W2910733642 hasConcept C137061746 @default.
• W2910733642 hasConcept C143998085 @default.
• W2910733642 hasConcept C145059251 @default.
• W2910733642 hasConcept C190283241 @default.
• W2910733642 hasConcept C202751555 @default.
• W2910733642 hasConcept C203014093 @default.
• W2910733642 hasConcept C2776256026 @default.
• W2910733642 hasConcept C48023723 @default.
• W2910733642 hasConcept C502942594 @default.
• W2910733642 hasConcept C54355233 @default.
• W2910733642 hasConcept C71924100 @default.
• W2910733642 hasConcept C86803240 @default.
• W2910733642 hasConcept C97037327 @default.
• W2910733642 hasConceptScore W2910733642C104317684 @default.
• W2910733642 hasConceptScore W2910733642C121608353 @default.
• W2910733642 hasConceptScore W2910733642C126322002 @default.
• W2910733642 hasConceptScore W2910733642C137061746 @default.
• W2910733642 hasConceptScore W2910733642C143998085 @default.
• W2910733642 hasConceptScore W2910733642C145059251 @default.
• W2910733642 hasConceptScore W2910733642C190283241 @default.
• W2910733642 hasConceptScore W2910733642C202751555 @default.
• W2910733642 hasConceptScore W2910733642C203014093 @default.
• W2910733642 hasConceptScore W2910733642C2776256026 @default.
• W2910733642 hasConceptScore W2910733642C48023723 @default.
• W2910733642 hasConceptScore W2910733642C502942594 @default.
• W2910733642 hasConceptScore W2910733642C54355233 @default.
• W2910733642 hasConceptScore W2910733642C71924100 @default.
• W2910733642 hasConceptScore W2910733642C86803240 @default.
• W2910733642 hasConceptScore W2910733642C97037327 @default.
• W2910733642 hasIssue "In Press" @default.
• W2910733642 hasLocation W29107336421 @default.
• W2910733642 hasLocation W29107336422 @default.
• W2910733642 hasOpenAccess W2910733642 @default.
• W2910733642 hasPrimaryLocation W29107336421 @default.
• W2910733642 hasRelatedWork W1991851561 @default.
• W2910733642 hasRelatedWork W2135855393 @default.

• next