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- W2910810437 abstract "The risk of hemorrhagic events in small ruptured aneurysms remains unclear. Due to less arterial wall, small ruptured aneurysms may be correlated with massive bleeding and rebleeding. Therefore, it may contribute to treatment to evaluate the amount of bleeding and the risk of rebleeding in small ruptured aneurysms.A retrospective cohort study of all consecutive patients with intracranial aneurysms admitted to our hospital from February 2013 to December 2017 was carried out. Ruptured aneurysms were divided into small ruptured aneurysm (0-5 mm) group and large ruptured aneurysm (5 mm) group for analysis. The difference of bleeding volume, rebleeding and clinical outcome were analyzed between the two groups.A total of 738 patients with aneurysmal subarachnoid hemorrhage (SAH) were included in this study and small ruptured aneurysms accounted for 49.2% of all ruptured aneurysms. Univariate analysis showed that the amount of bleeding (14.5 ± 7.1 vs. 14.4 ± 7.3; P = 0.867), rebleeding (8.3% vs. 10.9%; P = 0.261) and poor outcome (29.6% vs. 23.1%; P = 0.055) were similar between the two groups. Multivariable analysis showed that hypertension was obviously associated with the amount of bleeding (adjusted odds ratio (aOR), 3.25 [1.81-4.69]; P < 0.001) and rebleeding (aOR, 3.31 [1.10-9.99]; P = 0.034) in small ruptured aneurysms, and its effect on rebleeding of small ruptured aneurysms is greater than that of large ruptured aneurysms.The risk of hemorrhagic events in small ruptured aneurysms is similar to that in large ruptured aneurysms, especially those patients with small ruptured aneurysms that complicated with hypertension are at an increased risk of massive SAH and rebleeding." @default.
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- W2910810437 date "2019-01-13" @default.
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- W2910810437 title "Small ruptured intracranial aneurysms: the risk of massive bleeding and rebleeding" @default.
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- W2910810437 doi "https://doi.org/10.1080/01616412.2018.1563737" @default.
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