FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2910842919> ?p ?o ?g. }

• W2910842919 endingPage "475" @default.
• W2910842919 startingPage "468" @default.
• W2910842919 abstract "Locally advanced squamous cell carcinoma of the head and neck (LASCCHN) is usually treated with cisplatin (CDDP)-based chemoradiotherapy, except when patients are elderly or have renal, cardiac, or neurogenic dysfunction. This study compared the safety and efficacy of concurrent carboplatin (CBDCA) to cetuximab (Cmab) plus radiotherapy (RT) in patients ineligible for CDDP treatment. We retrospectively analyzed LASCCHN patients who received CBDCA plus RT (n = 29) or Cmab plus RT (n = 18) due to ineligibility for CDDP treatment at two Japanese institutions between August 2006 and December 2015. Patients characteristics for CBDCA plus RT and Cmab plus RT were: median age, 74 and 75 years; 0–1 performance status, 90% and 100%; main primary tumor site, hypopharynx 52% (n = 15) and oropharynx 39% (n = 7); and stage IV, 90% (n = 26) and 50% (n = 9), respectively. With a median follow-up time of 60.0 months for CBDCA plus RT and 53.6 months for Cmab plus RT, 3-year locoregional control rates were 56% versus 58%, and median progression-free survival was 42.7 versus 11.6 months. CBDCA plus RT was associated with more grade 3/4 hematologic toxicities, including neutropenia and thrombocytopenia, whereas Cmab plus RT was associated with more grade 3/4 oral mucositis and radiation dermatitis. CBDCA or Cmab as a concurrent systemic therapy with RT is a possible treatment option for LASCCHN patients ineligible for CDDP treatment, although attention to hematological toxicity should be paid." @default.
• W2910842919 created "2019-01-25" @default.
• W2910842919 creator A5000636193 @default.
• W2910842919 creator A5011388151 @default.
• W2910842919 creator A5017656239 @default.
• W2910842919 creator A5024159668 @default.
• W2910842919 creator A5028998584 @default.
• W2910842919 creator A5037615355 @default.
• W2910842919 creator A5050345537 @default.
• W2910842919 creator A5066514747 @default.
• W2910842919 creator A5066761673 @default.
• W2910842919 creator A5069640225 @default.
• W2910842919 creator A5075797504 @default.
• W2910842919 creator A5076314944 @default.
• W2910842919 date "2019-01-17" @default.
• W2910842919 modified "2023-10-16" @default.
• W2910842919 title "Safety and efficacy of concurrent carboplatin or cetuximab plus radiotherapy for locally advanced head and neck cancer patients ineligible for treatment with cisplatin" @default.
• W2910842919 cites W1974227785 @default.
• W2910842919 cites W1977306578 @default.
• W2910842919 cites W1987671229 @default.
• W2910842919 cites W1990441347 @default.
• W2910842919 cites W2036005555 @default.
• W2910842919 cites W2072802417 @default.
• W2910842919 cites W2083302423 @default.
• W2910842919 cites W2089257078 @default.
• W2910842919 cites W2095870363 @default.
• W2910842919 cites W2132017941 @default.
• W2910842919 cites W2133157486 @default.
• W2910842919 cites W2141044315 @default.
• W2910842919 cites W2141592118 @default.
• W2910842919 cites W2146148650 @default.
• W2910842919 cites W2146955099 @default.
• W2910842919 cites W2147869809 @default.
• W2910842919 cites W2150387405 @default.
• W2910842919 cites W2151730005 @default.
• W2910842919 cites W2155384808 @default.
• W2910842919 cites W2162629228 @default.
• W2910842919 cites W2172481603 @default.
• W2910842919 cites W2177098632 @default.
• W2910842919 cites W2194286561 @default.
• W2910842919 cites W2269740635 @default.
• W2910842919 cites W2277099308 @default.
• W2910842919 cites W2740752435 @default.
• W2910842919 doi "https://doi.org/10.1007/s10147-018-01392-9" @default.
• W2910842919 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30656463" @default.
• W2910842919 hasPublicationYear "2019" @default.
• W2910842919 type Work @default.
• W2910842919 sameAs 2910842919 @default.
• W2910842919 citedByCount "16" @default.
• W2910842919 countsByYear W29108429192019 @default.
• W2910842919 countsByYear W29108429192020 @default.
• W2910842919 countsByYear W29108429192021 @default.
• W2910842919 countsByYear W29108429192022 @default.
• W2910842919 countsByYear W29108429192023 @default.
• W2910842919 crossrefType "journal-article" @default.
• W2910842919 hasAuthorship W2910842919A5000636193 @default.
• W2910842919 hasAuthorship W2910842919A5011388151 @default.
• W2910842919 hasAuthorship W2910842919A5017656239 @default.
• W2910842919 hasAuthorship W2910842919A5024159668 @default.
• W2910842919 hasAuthorship W2910842919A5028998584 @default.
• W2910842919 hasAuthorship W2910842919A5037615355 @default.
• W2910842919 hasAuthorship W2910842919A5050345537 @default.
• W2910842919 hasAuthorship W2910842919A5066514747 @default.
• W2910842919 hasAuthorship W2910842919A5066761673 @default.
• W2910842919 hasAuthorship W2910842919A5069640225 @default.
• W2910842919 hasAuthorship W2910842919A5075797504 @default.
• W2910842919 hasAuthorship W2910842919A5076314944 @default.
• W2910842919 hasBestOaLocation W29108429192 @default.
• W2910842919 hasConcept C121608353 @default.
• W2910842919 hasConcept C126322002 @default.
• W2910842919 hasConcept C143998085 @default.
• W2910842919 hasConcept C2776530083 @default.
• W2910842919 hasConcept C2776694085 @default.
• W2910842919 hasConcept C2776833033 @default.
• W2910842919 hasConcept C2777063308 @default.
• W2910842919 hasConcept C2778239845 @default.
• W2910842919 hasConcept C2778424827 @default.
• W2910842919 hasConcept C2778496288 @default.
• W2910842919 hasConcept C2779998722 @default.
• W2910842919 hasConcept C2780140570 @default.
• W2910842919 hasConcept C2781451048 @default.
• W2910842919 hasConcept C509974204 @default.
• W2910842919 hasConcept C526805850 @default.
• W2910842919 hasConcept C71924100 @default.
• W2910842919 hasConcept C90924648 @default.
• W2910842919 hasConceptScore W2910842919C121608353 @default.
• W2910842919 hasConceptScore W2910842919C126322002 @default.
• W2910842919 hasConceptScore W2910842919C143998085 @default.
• W2910842919 hasConceptScore W2910842919C2776530083 @default.
• W2910842919 hasConceptScore W2910842919C2776694085 @default.
• W2910842919 hasConceptScore W2910842919C2776833033 @default.
• W2910842919 hasConceptScore W2910842919C2777063308 @default.
• W2910842919 hasConceptScore W2910842919C2778239845 @default.
• W2910842919 hasConceptScore W2910842919C2778424827 @default.
• W2910842919 hasConceptScore W2910842919C2778496288 @default.
• W2910842919 hasConceptScore W2910842919C2779998722 @default.
• W2910842919 hasConceptScore W2910842919C2780140570 @default.
• W2910842919 hasConceptScore W2910842919C2781451048 @default.

• next