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- W2910909841 abstract "Aim. To evaluate the effcacy of statin therapy in patients with acute coronary syndrome in real clinical practice and to develop the monitoring of the quality of patients’ management. Methods. 255 patients with acute coronary syndrome who have undergone stenting of the infarct-related coronary artery were included in the study using the continuous sampling method. The follow-up period was 12 months. All the patients received atorvastatin at a dose of 20 mg were included in the «Omsk Segion State Program» (Program) – the control group. The comparison group consisted of 112 patients with acute coronary syndrome who have undergone the stenting of the infarctrelated coronary artery, but who were not included in the Program and were routinely prescribed statins by general practitioners in the outpatient settings. Medical record abstracts and outpatient medical records were analyzed to estimate prescribed statin therapy regimens and clinical and laboratory fndings. The experts analyzed real clinical practice of statin prescription and monitored its effcacy and safety according to the recent guidelines on dyslipidemia. A novel method for improving the quality of statin therapy has been developed and introduced. Statistical analysis was processed using biometric statistical methods. Results. We found that cardiologists (control group) and general practitioners (comparison group) had low adherence to the current guidelines on dyslipidemia. The effcacy and safety of statin therapy regimens and duration were not monitored. Only 9.8% of patients in the control group and 3.6% of the patients in the comparison group achieved the target levels of low-density lipoprotein cholesterol (less than 1.8 mmol/l) within the 12-month follow-up (p = 0.096). Conclusion. Healthcare professionals’ low adherence to the current guidelines on dyslipidemia led to the need to develop the monitoring of the quality of patients’ management within 12 months after acute coronary syndrome." @default.
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- W2910909841 date "2018-12-18" @default.
- W2910909841 modified "2023-09-27" @default.
- W2910909841 title "STATIN THERAPY AFTER ACUTE CORONARY SYNDROME: LESSONS OF REAL CLINICAL PRACTICE" @default.
- W2910909841 doi "https://doi.org/10.17802/2306-1278-2018-7-4-77-83" @default.
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