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- W2910924861 abstract "Abstract Scopolia tangutica is a traditional Chinese medicine used for antispasmodic, anesthesia, analgesia, and sedation. Its medicinal activity is associated to alkaloid constituents, including tropane and cinnamamide types. Low content of alkaloids in plant makes them difficult to be isolated and identified. The present work developed an effective method to quickly characterize alkaloids from Scopolia tangutica by high‐performance liquid chromatography coupled with quadrupole time‐of‐flight tandem mass spectrometry. Thirteen reference compounds were studied for their fragmentation pathways, including five tropane alkaloids and eight cinnamamide ones. Alkaloid constituent was analyzed by an optimized high‐performance liquid chromatography method and mass spectrometry analysis to achieve systematic characterization of alkaloids from Scopolia tangutica . As a result, 53 compounds were identified, including 21 tropane alkaloids (eight new ones), 18 caffeoyl ones (ten new ones) and 14 dicaffeoyl ones (seven new ones). It was important to provide rich information in phytochemical study and structure‐guided isolation of important compounds from this plant." @default.
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- W2910924861 date "2019-01-30" @default.
- W2910924861 modified "2023-10-17" @default.
- W2910924861 title "Characterization of tropane and cinnamamide alkaloids from <i>Scopolia tangutica</i> by high‐performance liquid chromatography with quadrupole time‐of‐flight tandem mass spectrometry" @default.
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- W2910924861 doi "https://doi.org/10.1002/jssc.201801201" @default.
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