FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2911254083> ?p ?o ?g. }

• W2911254083 endingPage "160" @default.
• W2911254083 startingPage "155" @default.
• W2911254083 abstract "Despite substantial increases in the use of antipsychotics to treat various psychiatric conditions in children, there is a lack of literature regarding long-term effects of early treatment. Some studies have indicated that early administration results in differential alterations to neurotransmission systems, but few studies have investigated whether there are long-term behavioral modifications. Therefore, the aim of the current study was to investigate the neurobehavioral effects of low dose risperidone (a commonly prescribed antipsychotic) treatment using juvenile rats. Twenty-four male Sprague-Dawley rats were either subcutaneously implanted with a continuous release risperidone pellet (.04 mg/day) or a placebo pellet. To encompass the peri-adolescent to adolescent timeframe (postnatal day 40-70) thought to be important for brain development, male rats began risperidone treatment at post-natal day 35. Six weeks following commencement of risperidone treatment, all rats were tested on a battery of behavioral assessments including open field, object recognition, Morris Water Maze, and Y-Maze tasks. Risperidone treatment did not affect performance on the open field, object recognition, or Morris Water maze. A significant effect was found on the Y-maze. Although all rats exhibited normal spontaneous alternation, risperidone treated rats demonstrated significantly higher same arm returns, indicative of a working memory deficit. Continued research is needed to determine whether early exposure to risperidone may lead to differences in working memory at longer time-points. These results seem to indicate that early low dose risperidone treatment during the peri-adolescent and adolescent period does not severely impair behavior." @default.
• W2911254083 created "2019-02-21" @default.
• W2911254083 creator A5064854006 @default.
• W2911254083 creator A5089189981 @default.
• W2911254083 date "2019-05-01" @default.
• W2911254083 modified "2023-09-26" @default.
• W2911254083 title "Neurobehavioral effects of chronic low-dose risperidone administration in juvenile male rats" @default.
• W2911254083 cites W1966037459 @default.
• W2911254083 cites W1969352530 @default.
• W2911254083 cites W1970056072 @default.
• W2911254083 cites W1975610252 @default.
• W2911254083 cites W1979700184 @default.
• W2911254083 cites W1980944036 @default.
• W2911254083 cites W1983245960 @default.
• W2911254083 cites W2004448469 @default.
• W2911254083 cites W2013936090 @default.
• W2911254083 cites W2017140635 @default.
• W2911254083 cites W2017169966 @default.
• W2911254083 cites W2034773912 @default.
• W2911254083 cites W2035565264 @default.
• W2911254083 cites W2045218440 @default.
• W2911254083 cites W2045538158 @default.
• W2911254083 cites W2050841927 @default.
• W2911254083 cites W2055517698 @default.
• W2911254083 cites W2060943331 @default.
• W2911254083 cites W2065341809 @default.
• W2911254083 cites W2068856152 @default.
• W2911254083 cites W2073793545 @default.
• W2911254083 cites W2074183548 @default.
• W2911254083 cites W2076733246 @default.
• W2911254083 cites W2080747161 @default.
• W2911254083 cites W2083048709 @default.
• W2911254083 cites W2099637930 @default.
• W2911254083 cites W2114487561 @default.
• W2911254083 cites W2118167672 @default.
• W2911254083 cites W2123403544 @default.
• W2911254083 cites W2129836160 @default.
• W2911254083 cites W2141683977 @default.
• W2911254083 cites W2143302321 @default.
• W2911254083 cites W2148399921 @default.
• W2911254083 cites W2168203121 @default.
• W2911254083 cites W2221715570 @default.
• W2911254083 cites W2328192696 @default.
• W2911254083 cites W2333454685 @default.
• W2911254083 cites W2406862447 @default.
• W2911254083 cites W2464801958 @default.
• W2911254083 cites W2478797866 @default.
• W2911254083 cites W2551031827 @default.
• W2911254083 cites W2561818014 @default.
• W2911254083 cites W2808141866 @default.
• W2911254083 cites W2830823453 @default.
• W2911254083 cites W2924293519 @default.
• W2911254083 cites W4247442089 @default.
• W2911254083 doi "https://doi.org/10.1016/j.bbr.2019.02.009" @default.
• W2911254083 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30735760" @default.
• W2911254083 hasPublicationYear "2019" @default.
• W2911254083 type Work @default.
• W2911254083 sameAs 2911254083 @default.
• W2911254083 citedByCount "5" @default.
• W2911254083 countsByYear W29112540832020 @default.
• W2911254083 countsByYear W29112540832021 @default.
• W2911254083 countsByYear W29112540832022 @default.
• W2911254083 countsByYear W29112540832023 @default.
• W2911254083 crossrefType "journal-article" @default.
• W2911254083 hasAuthorship W2911254083A5064854006 @default.
• W2911254083 hasAuthorship W2911254083A5089189981 @default.
• W2911254083 hasConcept C118552586 @default.
• W2911254083 hasConcept C126322002 @default.
• W2911254083 hasConcept C15744967 @default.
• W2911254083 hasConcept C169760540 @default.
• W2911254083 hasConcept C173586616 @default.
• W2911254083 hasConcept C2775847253 @default.
• W2911254083 hasConcept C2776412080 @default.
• W2911254083 hasConcept C2776921671 @default.
• W2911254083 hasConcept C2779085643 @default.
• W2911254083 hasConcept C2780057945 @default.
• W2911254083 hasConcept C2780494398 @default.
• W2911254083 hasConcept C2781161787 @default.
• W2911254083 hasConcept C42219234 @default.
• W2911254083 hasConcept C44752575 @default.
• W2911254083 hasConcept C558461103 @default.
• W2911254083 hasConcept C71924100 @default.
• W2911254083 hasConceptScore W2911254083C118552586 @default.
• W2911254083 hasConceptScore W2911254083C126322002 @default.
• W2911254083 hasConceptScore W2911254083C15744967 @default.
• W2911254083 hasConceptScore W2911254083C169760540 @default.
• W2911254083 hasConceptScore W2911254083C173586616 @default.
• W2911254083 hasConceptScore W2911254083C2775847253 @default.
• W2911254083 hasConceptScore W2911254083C2776412080 @default.
• W2911254083 hasConceptScore W2911254083C2776921671 @default.
• W2911254083 hasConceptScore W2911254083C2779085643 @default.
• W2911254083 hasConceptScore W2911254083C2780057945 @default.
• W2911254083 hasConceptScore W2911254083C2780494398 @default.
• W2911254083 hasConceptScore W2911254083C2781161787 @default.
• W2911254083 hasConceptScore W2911254083C42219234 @default.
• W2911254083 hasConceptScore W2911254083C44752575 @default.
• W2911254083 hasConceptScore W2911254083C558461103 @default.
• W2911254083 hasConceptScore W2911254083C71924100 @default.

• next