FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2911299512> ?p ?o ?g. }

• W2911299512 endingPage "404" @default.
• W2911299512 startingPage "401" @default.
• W2911299512 abstract "Background: Lamotrigine has become the most frequently prescribed drug in the treatment of pregnant women with epilepsy. Although some relevant studies have found a wide milk/maternal serum as well as infant/maternal serum concentration ratio, different infant ages at the time of sampling and small number of patients preclude comparison. The aim of this study was to provide a consistent evaluation. Methods: Data of 43 nursing women treated by lamotrigine were evaluated retrospectively. The authors followed the transport of lamotrigine during the first postnatal month from mothers to breastfed infants through maternal milk between the years 2002 and 2017. Results: Lamotrigine concentrations varied from 1.1 to 14.9 mg/L in the maternal serum, from <0.66 to 9.1 mg/L in the milk and between <0.66 and 6.9 mg/L in the infant serum. The milk/maternal serum concentration ratio ranged from <0.18 to 0.74 and the infant/maternal serum concentration ratio measured between <0.15 and 0.74. Highly significant correlations were found between milk and maternal serum levels and between infant serum levels and milk, maternal serum levels, lamotrigine daily dose, and also maternal dose related to the body weight. Conclusions: The authors confirmed the wide range of the milk/maternal serum concentration ratio and the infant/maternal serum concentration ratio. Although the degree of lamotrigine exposure to the breastfed infants was smaller than during gestation, 16% of the infant serum levels measured were within the therapeutic range used for the general epileptic population. Lamotrigine concentration monitoring in breastfed infant, in our opinion, is the most relevant aspect for the analysis of actual lamotrigine exposure in infants, especially in those with clinical symptoms." @default.
• W2911299512 created "2019-02-21" @default.
• W2911299512 creator A5018692145 @default.
• W2911299512 creator A5038770128 @default.
• W2911299512 creator A5052372415 @default.
• W2911299512 date "2019-06-01" @default.
• W2911299512 modified "2023-10-12" @default.
• W2911299512 title "A Short Communication: Lamotrigine Levels in Milk, Mothers, and Breastfed Infants During the First Postnatal Month" @default.
• W2911299512 cites W1977882333 @default.
• W2911299512 cites W1984774530 @default.
• W2911299512 cites W1993065415 @default.
• W2911299512 cites W2026506987 @default.
• W2911299512 cites W2040710422 @default.
• W2911299512 cites W2049673227 @default.
• W2911299512 cites W2063827237 @default.
• W2911299512 cites W2071397892 @default.
• W2911299512 cites W2074031792 @default.
• W2911299512 cites W2091583140 @default.
• W2911299512 cites W2091755901 @default.
• W2911299512 cites W2092034463 @default.
• W2911299512 cites W2134200996 @default.
• W2911299512 cites W2145807729 @default.
• W2911299512 cites W2147371468 @default.
• W2911299512 cites W2150070653 @default.
• W2911299512 cites W2159949206 @default.
• W2911299512 cites W2165103536 @default.
• W2911299512 cites W2186092389 @default.
• W2911299512 cites W2295944599 @default.
• W2911299512 cites W2314265286 @default.
• W2911299512 cites W2733990257 @default.
• W2911299512 cites W2783213694 @default.
• W2911299512 cites W2922074526 @default.
• W2911299512 doi "https://doi.org/10.1097/ftd.0000000000000604" @default.
• W2911299512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30688868" @default.
• W2911299512 hasPublicationYear "2019" @default.
• W2911299512 type Work @default.
• W2911299512 sameAs 2911299512 @default.
• W2911299512 citedByCount "6" @default.
• W2911299512 countsByYear W29112995122019 @default.
• W2911299512 countsByYear W29112995122020 @default.
• W2911299512 countsByYear W29112995122021 @default.
• W2911299512 countsByYear W29112995122022 @default.
• W2911299512 crossrefType "journal-article" @default.
• W2911299512 hasAuthorship W2911299512A5018692145 @default.
• W2911299512 hasAuthorship W2911299512A5038770128 @default.
• W2911299512 hasAuthorship W2911299512A5052372415 @default.
• W2911299512 hasConcept C118552586 @default.
• W2911299512 hasConcept C134018914 @default.
• W2911299512 hasConcept C185592680 @default.
• W2911299512 hasConcept C187212893 @default.
• W2911299512 hasConcept C2775871700 @default.
• W2911299512 hasConcept C2776283161 @default.
• W2911299512 hasConcept C2778186239 @default.
• W2911299512 hasConcept C2778802184 @default.
• W2911299512 hasConcept C2779234561 @default.
• W2911299512 hasConcept C3020081911 @default.
• W2911299512 hasConcept C3020294031 @default.
• W2911299512 hasConcept C42407357 @default.
• W2911299512 hasConcept C46973012 @default.
• W2911299512 hasConcept C54355233 @default.
• W2911299512 hasConcept C55493867 @default.
• W2911299512 hasConcept C71924100 @default.
• W2911299512 hasConcept C86803240 @default.
• W2911299512 hasConceptScore W2911299512C118552586 @default.
• W2911299512 hasConceptScore W2911299512C134018914 @default.
• W2911299512 hasConceptScore W2911299512C185592680 @default.
• W2911299512 hasConceptScore W2911299512C187212893 @default.
• W2911299512 hasConceptScore W2911299512C2775871700 @default.
• W2911299512 hasConceptScore W2911299512C2776283161 @default.
• W2911299512 hasConceptScore W2911299512C2778186239 @default.
• W2911299512 hasConceptScore W2911299512C2778802184 @default.
• W2911299512 hasConceptScore W2911299512C2779234561 @default.
• W2911299512 hasConceptScore W2911299512C3020081911 @default.
• W2911299512 hasConceptScore W2911299512C3020294031 @default.
• W2911299512 hasConceptScore W2911299512C42407357 @default.
• W2911299512 hasConceptScore W2911299512C46973012 @default.
• W2911299512 hasConceptScore W2911299512C54355233 @default.
• W2911299512 hasConceptScore W2911299512C55493867 @default.
• W2911299512 hasConceptScore W2911299512C71924100 @default.
• W2911299512 hasConceptScore W2911299512C86803240 @default.
• W2911299512 hasIssue "3" @default.
• W2911299512 hasLocation W29112995121 @default.
• W2911299512 hasLocation W29112995122 @default.
• W2911299512 hasOpenAccess W2911299512 @default.
• W2911299512 hasPrimaryLocation W29112995121 @default.
• W2911299512 hasRelatedWork W1972708677 @default.
• W2911299512 hasRelatedWork W2000762933 @default.
• W2911299512 hasRelatedWork W2037537532 @default.
• W2911299512 hasRelatedWork W2081889687 @default.
• W2911299512 hasRelatedWork W2132868609 @default.
• W2911299512 hasRelatedWork W2388163103 @default.
• W2911299512 hasRelatedWork W2473518677 @default.
• W2911299512 hasRelatedWork W2754366503 @default.
• W2911299512 hasRelatedWork W4298297087 @default.
• W2911299512 hasRelatedWork W4312231137 @default.
• W2911299512 hasVolume "41" @default.
• W2911299512 isParatext "false" @default.
• W2911299512 isRetracted "false" @default.

• next