FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2911345462> ?p ?o ?g. }

• W2911345462 endingPage "8" @default.
• W2911345462 startingPage "1" @default.
• W2911345462 abstract "Lymphocytic choriomeningitis virus (LCMV) is a rodent disease that can be transmitted to humans. A majority of persons infected with LCMV have only minor symptoms; however, it can cross the placental barrier during pregnancy and cause congenital defects in the fetus. Some viral infections early in gestation are hypothesized to lead to worse outcomes compared to those acquired during late gestation; however, LCMV has not been studied in this context. In the present study, differences in immunomodulation between the first- and third-trimester placental explants infected with LCMV were measured. LCMV replication was observed in the first-trimester chorionic villi, but not in term. The term placenta exhibited a robust innate immune response to infection by LCMV, marked by induction of ifn - α , il - 6 , and tnf - α gene expression which was not seen in the first-trimester explants. Cytokine secretion was also only seen in term explants. The results indicate that the first-trimester and term placentas differ in their permissiveness for LCMV infection, inversely correlating with the innate antiviral responses. This has implications for developing effective mechanisms that protect the fetus from infection based on stage of development." @default.
• W2911345462 created "2019-02-21" @default.
• W2911345462 creator A5060217762 @default.
• W2911345462 creator A5068046530 @default.
• W2911345462 date "2019-02-07" @default.
• W2911345462 modified "2023-10-14" @default.
• W2911345462 title "Lymphocytic Choriomeningitis Virus Infection Demonstrates Higher Replicative Capacity and Decreased Antiviral Response in the First-Trimester Placenta" @default.
• W2911345462 cites W105057087 @default.
• W2911345462 cites W136406978 @default.
• W2911345462 cites W1548730546 @default.
• W2911345462 cites W1971576406 @default.
• W2911345462 cites W1977040336 @default.
• W2911345462 cites W1981646935 @default.
• W2911345462 cites W1993019483 @default.
• W2911345462 cites W2007603900 @default.
• W2911345462 cites W2015065552 @default.
• W2911345462 cites W2028733896 @default.
• W2911345462 cites W2051887848 @default.
• W2911345462 cites W2054154317 @default.
• W2911345462 cites W2059577862 @default.
• W2911345462 cites W2077476596 @default.
• W2911345462 cites W2083685654 @default.
• W2911345462 cites W2087087751 @default.
• W2911345462 cites W2094761218 @default.
• W2911345462 cites W2097530324 @default.
• W2911345462 cites W2101961932 @default.
• W2911345462 cites W2132951370 @default.
• W2911345462 cites W2147381934 @default.
• W2911345462 cites W2150114245 @default.
• W2911345462 cites W2154957091 @default.
• W2911345462 cites W2329575514 @default.
• W2911345462 cites W2384699986 @default.
• W2911345462 cites W2423421007 @default.
• W2911345462 cites W2592072569 @default.
• W2911345462 cites W2604239467 @default.
• W2911345462 cites W2781472954 @default.
• W2911345462 doi "https://doi.org/10.1155/2019/7375217" @default.
• W2911345462 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6383429" @default.
• W2911345462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30882005" @default.
• W2911345462 hasPublicationYear "2019" @default.
• W2911345462 type Work @default.
• W2911345462 sameAs 2911345462 @default.
• W2911345462 citedByCount "6" @default.
• W2911345462 countsByYear W29113454622021 @default.
• W2911345462 countsByYear W29113454622022 @default.
• W2911345462 crossrefType "journal-article" @default.
• W2911345462 hasAuthorship W2911345462A5060217762 @default.
• W2911345462 hasAuthorship W2911345462A5068046530 @default.
• W2911345462 hasBestOaLocation W29113454621 @default.
• W2911345462 hasConcept C140704245 @default.
• W2911345462 hasConcept C151730666 @default.
• W2911345462 hasConcept C159047783 @default.
• W2911345462 hasConcept C167672396 @default.
• W2911345462 hasConcept C172680121 @default.
• W2911345462 hasConcept C203014093 @default.
• W2911345462 hasConcept C2522874641 @default.
• W2911345462 hasConcept C2776953305 @default.
• W2911345462 hasConcept C2777890099 @default.
• W2911345462 hasConcept C2779234561 @default.
• W2911345462 hasConcept C2779343474 @default.
• W2911345462 hasConcept C2780190958 @default.
• W2911345462 hasConcept C54355233 @default.
• W2911345462 hasConcept C86803240 @default.
• W2911345462 hasConcept C8891405 @default.
• W2911345462 hasConceptScore W2911345462C140704245 @default.
• W2911345462 hasConceptScore W2911345462C151730666 @default.
• W2911345462 hasConceptScore W2911345462C159047783 @default.
• W2911345462 hasConceptScore W2911345462C167672396 @default.
• W2911345462 hasConceptScore W2911345462C172680121 @default.
• W2911345462 hasConceptScore W2911345462C203014093 @default.
• W2911345462 hasConceptScore W2911345462C2522874641 @default.
• W2911345462 hasConceptScore W2911345462C2776953305 @default.
• W2911345462 hasConceptScore W2911345462C2777890099 @default.
• W2911345462 hasConceptScore W2911345462C2779234561 @default.
• W2911345462 hasConceptScore W2911345462C2779343474 @default.
• W2911345462 hasConceptScore W2911345462C2780190958 @default.
• W2911345462 hasConceptScore W2911345462C54355233 @default.
• W2911345462 hasConceptScore W2911345462C86803240 @default.
• W2911345462 hasConceptScore W2911345462C8891405 @default.
• W2911345462 hasFunder F4320310135 @default.
• W2911345462 hasLocation W29113454621 @default.
• W2911345462 hasLocation W29113454622 @default.
• W2911345462 hasLocation W29113454623 @default.
• W2911345462 hasLocation W29113454624 @default.
• W2911345462 hasLocation W29113454625 @default.
• W2911345462 hasOpenAccess W2911345462 @default.
• W2911345462 hasPrimaryLocation W29113454621 @default.
• W2911345462 hasRelatedWork W1409541451 @default.
• W2911345462 hasRelatedWork W1598089960 @default.
• W2911345462 hasRelatedWork W2040099078 @default.
• W2911345462 hasRelatedWork W2096931909 @default.
• W2911345462 hasRelatedWork W2139983200 @default.
• W2911345462 hasRelatedWork W2156242955 @default.
• W2911345462 hasRelatedWork W2163549884 @default.
• W2911345462 hasRelatedWork W2171386548 @default.
• W2911345462 hasRelatedWork W2406270448 @default.
• W2911345462 hasRelatedWork W2809225164 @default.
• W2911345462 hasVolume "2019" @default.

• next