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- W2911398540 abstract "Objective: The goal of this work was to create implantable stimulator systems that could be used in animal experiments on laryngeal paralysis, including “closed-loop” stimulation of impaired muscles triggered by electromyographic (EMG) potentials from healthy muscles. Study Design: Iterative device design and testing. Methods: A series of microcontroller-based implantable devices were built that incorporated increasingly sophisticated features for stimulation, EMG recording, and communication across the skin. Specific engineering challenges included minimizing power consumption, achieving charge-balanced and relatively high stimulation capacity, implementing noninvasive communication across the skin, providing real-time processing of EMG signals, and mitigating effects of shock artifacts. Bench testing was used to verify performance. Results: Two prototypes are described in detail. Each system is based on an “implant” and an external “communication adapter” that interfaces both with the implant and with external computers for adjustments and monitoring. The first version described is inductively powered and referred to as the “inductive laryngeal stimulator.” It uses inductive coupling for both power and communication and performs EMG processing in the communication adapter module. The second version, a “battery-powered laryngeal stimulator,” consists of an autonomous battery-powered implant with onboard EMG processing and artifact control; it communicates by infrared light with the external communication adapter for setup and monitoring. Conclusions: The devices met design and performance specifications and have proved useful in the animal experiments that are described in Part 2 of this series. Detailed descriptions of the circuits and their firmware are made available in the Appendix. Level of Evidence: NA" @default.
- W2911398540 created "2019-02-21" @default.
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- W2911398540 date "2019-01-27" @default.
- W2911398540 modified "2023-09-24" @default.
- W2911398540 title "Development of a Closed-Loop Stimulator for Laryngeal Reanimation, Part 1: Devices" @default.
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- W2911398540 doi "https://doi.org/10.1177/0003489418820885" @default.
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