FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2911402208> ?p ?o ?g. }

• W2911402208 endingPage "901" @default.
• W2911402208 startingPage "890" @default.
• W2911402208 abstract "Since 2010, the Chinese have become one of the most aged populations in the world, leading to a severe burden of neurodegenerative disorders. Alzheimer's disease (AD) is the most prevalent neurodegenerative disease and has a high genetic heritability. In the past two decades, numerous genetic analyses, from linkage analyses and candidate gene studies to genome-wide association studies (GWASs) and next-generation sequencing studies, have identified dozens of AD susceptibility or causal genes. These studies have provided a comprehensive genetic view and contributed to the understanding of the pathological and molecular mechanisms of the disease. However, most of the recognized AD genetic risk factors have been reported in studies based on European populations or populations of European ancestry, and data about the genetics of AD from other populations has been very limited. As China has the largest AD population in the world and because of the remarkable genetic differences between the East and the West, deciphering the genetic basis and molecular mechanism in Chinese patients with AD may add key points to the full characterization of AD. In this review, we present an overview of the current state of AD genetic research in China, with an emphasis on genome-level studies. We also describe the challenges and opportunities for future advances, especially for in-depth collaborations, brain bank construction, and primate animal modeling. There is an urgent need to promote public awareness and increase our collaborations and data sharing." @default.
• W2911402208 created "2019-02-21" @default.
• W2911402208 creator A5003365817 @default.
• W2911402208 creator A5011554341 @default.
• W2911402208 creator A5066652935 @default.
• W2911402208 creator A5083791483 @default.
• W2911402208 date "2019-01-30" @default.
• W2911402208 modified "2023-10-18" @default.
• W2911402208 title "Genetic Analyses of Alzheimer’s Disease in China: Achievements and Perspectives" @default.
• W2911402208 cites W1552188451 @default.
• W2911402208 cites W1563064469 @default.
• W2911402208 cites W1759520601 @default.
• W2911402208 cites W1890431460 @default.
• W2911402208 cites W1923740474 @default.
• W2911402208 cites W1974826026 @default.
• W2911402208 cites W1983693972 @default.
• W2911402208 cites W1996406602 @default.
• W2911402208 cites W1999837492 @default.
• W2911402208 cites W2001369631 @default.
• W2911402208 cites W2004788163 @default.
• W2911402208 cites W2005972093 @default.
• W2911402208 cites W2013237964 @default.
• W2911402208 cites W2017079501 @default.
• W2911402208 cites W2017581860 @default.
• W2911402208 cites W2018342879 @default.
• W2911402208 cites W2018763082 @default.
• W2911402208 cites W2030641075 @default.
• W2911402208 cites W2035691398 @default.
• W2911402208 cites W2040104792 @default.
• W2911402208 cites W2041573647 @default.
• W2911402208 cites W2042169915 @default.
• W2911402208 cites W2045153164 @default.
• W2911402208 cites W2045508278 @default.
• W2911402208 cites W2046209489 @default.
• W2911402208 cites W2051388479 @default.
• W2911402208 cites W2053571233 @default.
• W2911402208 cites W2058723245 @default.
• W2911402208 cites W2065792884 @default.
• W2911402208 cites W2072074212 @default.
• W2911402208 cites W2075353928 @default.
• W2911402208 cites W2076890848 @default.
• W2911402208 cites W2083633251 @default.
• W2911402208 cites W2091174457 @default.
• W2911402208 cites W2099248872 @default.
• W2911402208 cites W2099802989 @default.
• W2911402208 cites W2108292688 @default.
• W2911402208 cites W2115779804 @default.
• W2911402208 cites W2128613449 @default.
• W2911402208 cites W2128931247 @default.
• W2911402208 cites W2131273916 @default.
• W2911402208 cites W2152119060 @default.
• W2911402208 cites W2154755614 @default.
• W2911402208 cites W2157233322 @default.
• W2911402208 cites W2162681653 @default.
• W2911402208 cites W2165644824 @default.
• W2911402208 cites W2166336042 @default.
• W2911402208 cites W2166966137 @default.
• W2911402208 cites W2169270398 @default.
• W2911402208 cites W2178866977 @default.
• W2911402208 cites W2180486725 @default.
• W2911402208 cites W2192805543 @default.
• W2911402208 cites W2193207784 @default.
• W2911402208 cites W2252925835 @default.
• W2911402208 cites W2261151942 @default.
• W2911402208 cites W2292528698 @default.
• W2911402208 cites W2344974984 @default.
• W2911402208 cites W2429713509 @default.
• W2911402208 cites W2483498315 @default.
• W2911402208 cites W2510750345 @default.
• W2911402208 cites W2518330113 @default.
• W2911402208 cites W2548266803 @default.
• W2911402208 cites W2559911659 @default.
• W2911402208 cites W2562281683 @default.
• W2911402208 cites W2576762795 @default.
• W2911402208 cites W2580976313 @default.
• W2911402208 cites W2592518050 @default.
• W2911402208 cites W2610900695 @default.
• W2911402208 cites W2615586834 @default.
• W2911402208 cites W2725988230 @default.
• W2911402208 cites W2734124434 @default.
• W2911402208 cites W2747562354 @default.
• W2911402208 cites W2754986420 @default.
• W2911402208 cites W2760285987 @default.
• W2911402208 cites W2760946750 @default.
• W2911402208 cites W2761271661 @default.
• W2911402208 cites W2782666039 @default.
• W2911402208 cites W2784769965 @default.
• W2911402208 cites W2787933178 @default.
• W2911402208 cites W2792688330 @default.
• W2911402208 cites W2793391328 @default.
• W2911402208 cites W2795037232 @default.
• W2911402208 cites W2795847116 @default.
• W2911402208 cites W2799913710 @default.
• W2911402208 cites W2801171287 @default.
• W2911402208 cites W2806429840 @default.
• W2911402208 cites W2839171862 @default.
• W2911402208 cites W2886126921 @default.
• W2911402208 cites W2886870891 @default.

• next