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- W2911409690 abstract "Introduction: Hepatocellular carcinoma (HCC) is the most common type of liver cancer. However, pharmacological approaches remain limited and currently available drugs can trigger resistance phenomena in many patients. Therefore, it is crucial the identification of new drugs and/or a second-line agent(s) that may act on multiple pathways that regulate HCC pathogenesis and its hheterogeneous nature. We recently unveil a novel unprecedented role of focal adhesion kinase (FAK) in HCC growth, thus it is conceivable that this protein could be a new target for anticancer therapies." @default.
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- W2911409690 date "2019-02-01" @default.
- W2911409690 modified "2023-09-25" @default.
- W2911409690 title "Combined therapy with Sorafenib and FAK inhibitor TAE226 impairs hepatocellular carcinoma growth by interfering with epigenetic modifications and stemness markers" @default.
- W2911409690 doi "https://doi.org/10.1016/j.dld.2018.11.102" @default.
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