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- W2911419586 abstract "Introduction: Non-alcoholic fatty pancreas disease (NAFPD) has been associated with the development of type 2 diabetes mellitus (DM2), increased acute pancreatitis severity and the development of pancreatic cancer. The aim of our study is to describe the association of NAFPD and prediabetes (PDM) in asymptomatic patients. Methods: Cross-sectional observational study from a single center in Mexico City. We defined NAFPD based on ultrasound features and alcohol consumption of less than 20 gr/day in men or 10 g/day in women. PDM was defined by impaired fasting glucose (IFG) after a 12 hour fast (with a glucose value of 100-125 mg/dL) and/or a glycated hemoglobin (A1C) test between 5.7 and 6.4 percent. Results: We included data from 458 asymptomatic ambulatory patients who underwent health check-up. The prevalence of NAFPD detected by ultrasound was 17.3% (95% CI, 13-20), and 37% of patients in this group had associated non-alcoholic fatty liver disease (NAFLD). The global prevalence of PDM was 26.6 % and 10/122 (91.8%) were newly detected cases, 62.7% were male, mean BMI was 26.02 (SD +/- 4.0) kg/m2. Patients with PDM had associated NAFPD [OR=2.8 (95% CI 1.025 - 7.8), P=0.038]. Conclusion: We found an association between NAFPD and PDM in asymptomatic outpatients. To our knowledge there have not been any such descriptions in our population. Prospective studies are required to determine the importance of pancreatic fat deposition and its consequences in Hispanics." @default.
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- W2911419586 date "2017-10-01" @default.
- W2911419586 modified "2023-09-27" @default.
- W2911419586 title "Non-alcoholic Fatty Pancreas Disease Is Associated With Prediabetes in Hispanics" @default.
- W2911419586 doi "https://doi.org/10.14309/00000434-201710001-00086" @default.
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