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• W2911421640 abstract "Abstract The use of the human reference genome has shaped methods and data across modern genomics. This has offered many benefits while creating a few constraints. In the following piece, we outline the history, properties, and pitfalls of the current human reference genome. In a few illustrative analyses, we focus on its use for variant-calling, highlighting its nearness to a “type specimen”. We suggest that switching to a consensus reference offers important advantages over the current reference with few disadvantages." @default.
• W2911421640 created "2019-02-21" @default.
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• W2911421640 date "2019-01-29" @default.
• W2911421640 modified "2023-09-24" @default.
• W2911421640 title "Is it time to change the reference genome?" @default.
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• W2911421640 doi "https://doi.org/10.1101/533166" @default.
• W2911421640 hasPublicationYear "2019" @default.
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