FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2911481310> ?p ?o ?g. }

• W2911481310 endingPage "73" @default.
• W2911481310 startingPage "65" @default.
• W2911481310 abstract "Myeloproliferative Neoplasms (MPNs) are a group of progressive diseases that share a common pathogenesis, clinical and laboratory features, as well as a spontaneous risk of secondary AML. Certain MPN therapies have been associated with an increased risk of leukemic conversion, with robust data highlighting the highest rates with 32P, chlorambucil, and pipobroman. Herein, we review risk factors for leukemic transformation, including therapy-related MPN-BP, with a focus on the debate surrounding the potential leukemogenicity of hydroxyurea. Lastly, we discuss emerging studies on the association between ruxolitinib and high grade B-cell lymphomas. We conclude that statistical associations have not implicated hydroxyurea monotherapy as leukemogenic. However, it is difficult to definitely disprove an association, as large prospective, controlled studies with decades of follow-up would be needed to draw conclusions. Overall, the concept of therapy-related neoplasms remains important to the field, and mandates judicious selection and sequencing of therapies for MPN patients." @default.
• W2911481310 created "2019-02-21" @default.
• W2911481310 creator A5022887326 @default.
• W2911481310 creator A5029951643 @default.
• W2911481310 date "2019-03-01" @default.
• W2911481310 modified "2023-10-13" @default.
• W2911481310 title "Therapy-associated leukemic transformation in myeloproliferative neoplasms – What do we know?" @default.
• W2911481310 cites W1421162947 @default.
• W2911481310 cites W1503652716 @default.
• W2911481310 cites W1821109160 @default.
• W2911481310 cites W1970111821 @default.
• W2911481310 cites W1976961587 @default.
• W2911481310 cites W1977590248 @default.
• W2911481310 cites W1984567268 @default.
• W2911481310 cites W1990444790 @default.
• W2911481310 cites W2014091629 @default.
• W2911481310 cites W2028961479 @default.
• W2911481310 cites W2030868349 @default.
• W2911481310 cites W2049145190 @default.
• W2911481310 cites W2052451894 @default.
• W2911481310 cites W2056116861 @default.
• W2911481310 cites W2065625658 @default.
• W2911481310 cites W2072881492 @default.
• W2911481310 cites W2076231724 @default.
• W2911481310 cites W2078483041 @default.
• W2911481310 cites W2085404468 @default.
• W2911481310 cites W2085677832 @default.
• W2911481310 cites W2099366696 @default.
• W2911481310 cites W2111141291 @default.
• W2911481310 cites W2112316414 @default.
• W2911481310 cites W2119941797 @default.
• W2911481310 cites W2122395736 @default.
• W2911481310 cites W2123587611 @default.
• W2911481310 cites W2138709799 @default.
• W2911481310 cites W2146505525 @default.
• W2911481310 cites W2149373649 @default.
• W2911481310 cites W2149927396 @default.
• W2911481310 cites W2153170459 @default.
• W2911481310 cites W2157694607 @default.
• W2911481310 cites W2157799454 @default.
• W2911481310 cites W2167851932 @default.
• W2911481310 cites W2170086069 @default.
• W2911481310 cites W2177570048 @default.
• W2911481310 cites W2306779733 @default.
• W2911481310 cites W2317624320 @default.
• W2911481310 cites W2491978007 @default.
• W2911481310 cites W2557590973 @default.
• W2911481310 cites W2621352951 @default.
• W2911481310 cites W2731573311 @default.
• W2911481310 cites W2732761160 @default.
• W2911481310 cites W2735582214 @default.
• W2911481310 cites W2768301539 @default.
• W2911481310 cites W2770174719 @default.
• W2911481310 cites W2775539199 @default.
• W2911481310 cites W2808491541 @default.
• W2911481310 cites W2885209153 @default.
• W2911481310 cites W2892675555 @default.
• W2911481310 cites W2896385413 @default.
• W2911481310 cites W2901309750 @default.
• W2911481310 cites W2907138491 @default.
• W2911481310 cites W3114368461 @default.
• W2911481310 cites W4214947912 @default.
• W2911481310 cites W4237200993 @default.
• W2911481310 cites W4249070388 @default.
• W2911481310 doi "https://doi.org/10.1016/j.beha.2019.02.004" @default.
• W2911481310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30927977" @default.
• W2911481310 hasPublicationYear "2019" @default.
• W2911481310 type Work @default.
• W2911481310 sameAs 2911481310 @default.
• W2911481310 citedByCount "13" @default.
• W2911481310 countsByYear W29114813102020 @default.
• W2911481310 countsByYear W29114813102022 @default.
• W2911481310 countsByYear W29114813102023 @default.
• W2911481310 crossrefType "journal-article" @default.
• W2911481310 hasAuthorship W2911481310A5022887326 @default.
• W2911481310 hasAuthorship W2911481310A5029951643 @default.
• W2911481310 hasConcept C126322002 @default.
• W2911481310 hasConcept C143998085 @default.
• W2911481310 hasConcept C2776112149 @default.
• W2911481310 hasConcept C2780007613 @default.
• W2911481310 hasConcept C2780076729 @default.
• W2911481310 hasConcept C2910274570 @default.
• W2911481310 hasConcept C60644358 @default.
• W2911481310 hasConcept C71924100 @default.
• W2911481310 hasConcept C86803240 @default.
• W2911481310 hasConceptScore W2911481310C126322002 @default.
• W2911481310 hasConceptScore W2911481310C143998085 @default.
• W2911481310 hasConceptScore W2911481310C2776112149 @default.
• W2911481310 hasConceptScore W2911481310C2780007613 @default.
• W2911481310 hasConceptScore W2911481310C2780076729 @default.
• W2911481310 hasConceptScore W2911481310C2910274570 @default.
• W2911481310 hasConceptScore W2911481310C60644358 @default.
• W2911481310 hasConceptScore W2911481310C71924100 @default.
• W2911481310 hasConceptScore W2911481310C86803240 @default.
• W2911481310 hasIssue "1" @default.
• W2911481310 hasLocation W29114813101 @default.
• W2911481310 hasLocation W29114813102 @default.
• W2911481310 hasOpenAccess W2911481310 @default.

• next